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TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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lipstick1438 products
foundation676 products
concealer462 products
eye shadow310 products
lip gloss295 products
beach & sport sunscreen265 products
moisturizer260 products
moisturizer with SPF239 products
blush223 products
facial moisturizer/treatment215 products
bronzer/highlighter211 products
conditioner202 products
serums & essences181 products
shampoo149 products
brow liner143 products
mascara122 products
mask119 products
body wash/cleanser114 products
liquid hand soap106 products
facial powder93 products
lip balm89 products
eye liner86 products
facial cleanser82 products
hair treatment/serum72 products
makeup primer70 products
around-eye cream58 products
bath oil/salts/soak58 products
baby wipes54 products
lip liner51 products
exfoliant/scrub51 products
makeup remover50 products
hand sanitizer49 products
lip balm with SPF49 products
hair styling aide45 products
body firming lotion42 products
shaving cream38 products
hand cream38 products
BB cream38 products
antiperspirant/deodorant30 products
anti-aging29 products
body oil28 products
CC cream28 products
24 products
lip plumper22 products
after sun product18 products
beard oil18 products
beard care18 products
toners/astringents18 products
bubble bath17 products
styling gel/lotion17 products
shaving cream (men's)16 products
hair color and bleaching15 products
polish remover15 products
bar soap15 products
baby lotion14 products
body spray14 products
diaper cream14 products
hair spray12 products
baby sunscreen12 products
fragrance for women11 products
foot moisturizer11 products
sunless tanning11 products
baby shampoo10 products
after shave10 products
makeup with SPF9 products
other eye makeup9 products
antiperspirant/deodorant (men's)9 products
nail treatment8 products
baby soap8 products
nail polish7 products
detangler6 products
foot cleansing6 products
baby oil5 products
damaged skin treatment5 products
oil controller5 products
toothpaste5 products
fragrance for men4 products
depilatory3 products
cuticle treatment3 products
eye makeup remover2 products
tanning oil2 products
baby powder2 products
muscle/joint soreness2 products
styling mousse/foam2 products
baby bubble bath2 products
hair relaxer2 products
foot odor control1 products
eyelash glue1 products
glitter1 products

Contamination concerns

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Chemical
HYDROQUINONE

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

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Concern Reference
tocopheryl acetate enhanced photocarcinogenesis in an animal studyGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer