TOCOPHERYL ACETATE
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Contamination concerns (high)
Cancer 

Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity 

Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity 

Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
lipstick | 1438 products |
foundation | 676 products |
concealer | 462 products |
eye shadow | 310 products |
lip gloss | 295 products |
beach & sport sunscreen | 265 products |
moisturizer | 260 products |
moisturizer with SPF | 239 products |
blush | 223 products |
facial moisturizer/treatment | 215 products |
bronzer/highlighter | 211 products |
conditioner | 202 products |
serums & essences | 181 products |
shampoo | 149 products |
brow liner | 143 products |
mascara | 122 products |
mask | 119 products |
body wash/cleanser | 114 products |
liquid hand soap | 106 products |
facial powder | 93 products |
lip balm | 89 products |
eye liner | 86 products |
facial cleanser | 82 products |
hair treatment/serum | 72 products |
makeup primer | 70 products |
around-eye cream | 58 products |
bath oil/salts/soak | 58 products |
baby wipes | 54 products |
lip liner | 51 products |
exfoliant/scrub | 51 products |
makeup remover | 50 products |
hand sanitizer | 49 products |
lip balm with SPF | 49 products |
hair styling aide | 45 products |
body firming lotion | 42 products |
shaving cream | 38 products |
hand cream | 38 products |
BB cream | 38 products |
antiperspirant/deodorant | 30 products |
anti-aging | 29 products |
body oil | 28 products |
CC cream | 28 products |
24 products | |
lip plumper | 22 products |
after sun product | 18 products |
beard oil | 18 products |
beard care | 18 products |
toners/astringents | 18 products |
bubble bath | 17 products |
styling gel/lotion | 17 products |
shaving cream (men's) | 16 products |
hair color and bleaching | 15 products |
polish remover | 15 products |
bar soap | 15 products |
baby lotion | 14 products |
body spray | 14 products |
diaper cream | 14 products |
hair spray | 12 products |
baby sunscreen | 12 products |
fragrance for women | 11 products |
foot moisturizer | 11 products |
sunless tanning | 11 products |
baby shampoo | 10 products |
after shave | 10 products |
makeup with SPF | 9 products |
other eye makeup | 9 products |
antiperspirant/deodorant (men's) | 9 products |
nail treatment | 8 products |
baby soap | 8 products |
nail polish | 7 products |
detangler | 6 products |
foot cleansing | 6 products |
baby oil | 5 products |
damaged skin treatment | 5 products |
oil controller | 5 products |
toothpaste | 5 products |
fragrance for men | 4 products |
depilatory | 3 products |
cuticle treatment | 3 products |
eye makeup remover | 2 products |
tanning oil | 2 products |
baby powder | 2 products |
muscle/joint soreness | 2 products |
styling mousse/foam | 2 products |
baby bubble bath | 2 products |
hair relaxer | 2 products |
foot odor control | 1 products |
eyelash glue | 1 products |
glitter | 1 products |
Contamination concerns
Chemical |
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HYDROQUINONE |
Allergies/immunotoxicity
Concern | Reference |
---|---|
Human skin toxicant or allergen - strong evidence | Cosmetic Ingredient Review Assessments |
Cancer
Concern | Reference |
---|---|
tocopheryl acetate enhanced photocarcinogenesis in an animal study | Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91. |
Ecotoxicology
Concern | Reference |
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Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation) | Environment Canada Domestic Substance List |
Uncertain environmental toxin and uncertain persistent or bioaccumulative | Environment Canada Domestic Substance List |
Data gaps
Concern | Reference |
---|---|
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments |
5742 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Multiple, additive exposure sources
Concern | Reference |
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Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Informational
Concern | Reference |
---|---|
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | Cosmetic Ingredient Review Assessments |
Organ system toxicity (non-reproductive)
Concern | Reference |
---|---|
Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Classified as a low human health priority | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
Concern | Reference |
---|---|
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer