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TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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lipstick1527 products
foundation795 products
concealer531 products
moisturizer378 products
lip gloss345 products
recreational sunscreen337 products
eye shadow330 products
daily use with SPF323 products
facial moisturizer/treatment311 products
conditioner306 products
bronzer/highlighter265 products
shampoo238 products
blush237 products
serums & essences215 products
body wash/cleanser186 products
mask176 products
brow liner163 products
liquid hand soap153 products
body firming lotion150 products
lip balm141 products
facial cleanser135 products
hair treatment/serum126 products
mascara116 products
facial powder107 products
makeup primer91 products
hand sanitizer86 products
eye liner81 products
exfoliant/scrub79 products
around-eye cream76 products
hair styling aide76 products
lip balm with SPF73 products
bath oil/salts/soak68 products
hand cream66 products
baby wipes65 products
shaving cream62 products
makeup remover60 products
anti-aging55 products
BB cream55 products
55 products
body oil53 products
antiperspirant/deodorant50 products
CC cream47 products
lip liner43 products
baby sunscreen42 products
after sun product41 products
setting powder/spray32 products
bar soap30 products
bubble bath29 products
sunless tanning29 products
polish remover27 products
shaving cream (men's)26 products
beard care26 products
hair spray25 products
baby shampoo25 products
styling gel/lotion24 products
lip plumper23 products
toners/astringents21 products
nail polish21 products
baby lotion20 products
foot moisturizer18 products
hair color and bleaching18 products
diaper cream18 products
beard oil18 products
after shave15 products
body spray15 products
antiperspirant/deodorant (men's)12 products
detangler12 products
fragrance for women12 products
nail treatment11 products
baby soap11 products
tanning oil10 products
other eye makeup9 products
styling mousse/foam8 products
baby oil8 products
baby powder7 products
foot cleansing7 products
damaged skin treatment7 products
fragrance for men7 products
cuticle treatment5 products
eye makeup remover5 products
oil controller5 products
toothpaste5 products
depilatory4 products
baby bubble bath3 products
glitter3 products
hair relaxer3 products
body powder2 products
hair-loss treatment2 products
muscle/joint soreness2 products
skin fading/lightener1 products
foot odor control1 products
beard cleanser1 products
eyelash glue1 products

Contamination concerns

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Chemical
HYDROQUINONE

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

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Concern Reference
tocopheryl acetate enhanced photocarcinogenesis in an animal studyGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

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Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer