Menu Close Menu

Menu

TOCOPHERYL ACETATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

Expand content Collapse content
lipstick892 products
foundation286 products
beach & sport sunscreen280 products
moisturizer with SPF272 products
concealer251 products
lip gloss160 products
eye shadow149 products
facial moisturizer/treatment130 products
moisturizer120 products
bronzer/highlighter114 products
serums & essences110 products
blush109 products
conditioner75 products
brow liner73 products
mask68 products
shampoo62 products
facial powder62 products
lip balm with SPF51 products
eye liner50 products
body wash/cleanser47 products
lip balm47 products
liquid hand soap43 products
facial cleanser40 products
around-eye cream35 products
mascara33 products
makeup primer29 products
BB cream27 products
hand cream23 products
exfoliant/scrub20 products
anti-aging19 products
makeup remover19 products
lip liner19 products
CC cream19 products
shaving cream18 products
hair treatment/serum16 products
baby sunscreen13 products
body firming lotion11 products
beard oil11 products
baby wipes10 products
baby lotion9 products
other eye makeup9 products
antiperspirant/deodorant9 products
lip plumper9 products
hair color and bleaching8 products
body oil8 products
sunless tanning8 products
bath oil/salts/soak7 products
shaving cream (men's)6 products
toothpaste6 products
after sun product6 products
toners/astringents6 products
hair styling aide6 products
hair spray5 products
body spray5 products
baby shampoo5 products
styling gel/lotion5 products
hand sanitizer5 products
oil controller5 products
bar soap4 products
after shave4 products
fragrance for women4 products
baby soap4 products
nail treatment3 products
polish remover2 products
baby oil2 products
antiperspirant/deodorant (men's)2 products
bubble bath2 products
makeup with SPF2 products
detangler2 products
nail polish2 products
baby powder1 products
eye makeup remover1 products
tanning oil1 products
eyelash glue1 products
damaged skin treatment1 products
foot moisturizer1 products
depilatory1 products
cuticle treatment1 products
hair relaxer1 products
styling mousse/foam1 products
fragrance for men1 products
foot odor control1 products

Contamination concerns

Expand content Collapse content
Chemical
HYDROQUINONE

Allergies/immunotoxicity

Expand content Collapse content
Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Cancer

Expand content Collapse content
Concern Reference
One or more animal studies show tumor formation at high dosesGensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.

Ecotoxicology

Expand content Collapse content
Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulative (uncertainty in environmental toxicity or persistence/bioaccumulation)Environment Canada Domestic Substance List
Uncertain environmental toxin and uncertain persistent or bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

Expand content Collapse content
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
5742 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

Expand content Collapse content
Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Gensler HL, Aickin M, Peng YM, Xu M 1996. Importance of the form of topical vitamin E for prevention of photocarcinogenesis. Nutr Cancer 26(2): 183-91.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer