Menu Close Menu

Menu

TOCOPHEROL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

Expand content Collapse content
beach & sport sunscreen851 products
lipstick735 products
foundation483 products
facial moisturizer/treatment412 products
moisturizer375 products
moisturizer with SPF321 products
lip balm316 products
concealer292 products
lip gloss254 products
serums & essences210 products
eye shadow161 products
lip balm with SPF159 products
bronzer/highlighter154 products
conditioner138 products
shampoo125 products
exfoliant/scrub124 products
lip liner116 products
facial cleanser115 products
eye liner114 products
blush103 products
baby sunscreen100 products
mask97 products
brow liner93 products
body wash/cleanser91 products
body firming lotion78 products
body oil77 products
antiperspirant/deodorant73 products
around-eye cream69 products
mascara68 products
hair treatment/serum50 products
facial powder48 products
makeup primer48 products
anti-aging44 products
hand cream44 products
hair color and bleaching37 products
BB cream36 products
bath oil/salts/soak34 products
baby lotion34 products
liquid hand soap32 products
Tanning Sprays30 products
hair styling aide29 products
makeup remover25 products
makeup with SPF24 products
bar soap23 products
CC cream22 products
styling gel/lotion22 products
Facial Sun Care21 products
beard oil20 products
toners/astringents20 products
shaving cream19 products
baby soap17 products
baby oil16 products
fragrance for women16 products
diaper cream14 products
other eye makeup13 products
sunless tanning12 products
toothpaste12 products
baby shampoo11 products
fragrance for men10 products
vapor rubs10 products
lip plumper9 products
shaving cream (men's)8 products
foot moisturizer8 products
after shave8 products
bubble bath7 products
eye makeup remover7 products
hair spray7 products
detangler6 products
baby wipes5 products
hand sanitizer5 products
styling mousse/foam4 products
after sun product4 products
cuticle treatment4 products
oil controller4 products
body spray4 products
antiperspirant/deodorant (men's)4 products
muscle/joint soreness3 products
other men's products3 products
nail treatment3 products
depilatory3 products
Lip Stain3 products
baby bubble bath2 products
mouthwash2 products
tanning oil1 products
skin fading/lightener1 products
baby powder1 products
foot odor control1 products
eyelash glue1 products
damaged skin treatment1 products
Under Eye Concealers1 products
polish remover1 products
Oils & Serums1 products

Contamination concerns

Expand content Collapse content
Chemical
HYDROQUINONE

Cancer

Expand content Collapse content
Concern Reference
One or more animal studies show tumor formation at high dosesConstantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.

Data gaps

Expand content Collapse content
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
43489 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

Expand content Collapse content
Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

Expand content Collapse content
Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Constantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer