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TOCOPHEROL
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Contamination concerns (high)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| beach & sport sunscreen | 848 products |
| lipstick | 734 products |
| foundation | 482 products |
| facial moisturizer/treatment | 412 products |
| moisturizer | 372 products |
| moisturizer with SPF | 321 products |
| lip balm | 313 products |
| concealer | 292 products |
| lip gloss | 253 products |
| serums & essences | 210 products |
| eye shadow | 161 products |
| lip balm with SPF | 159 products |
| bronzer/highlighter | 153 products |
| conditioner | 138 products |
| shampoo | 125 products |
| exfoliant/scrub | 123 products |
| eye liner | 114 products |
| facial cleanser | 114 products |
| lip liner | 113 products |
| blush | 103 products |
| baby sunscreen | 99 products |
| mask | 95 products |
| brow liner | 92 products |
| body wash/cleanser | 91 products |
| body oil | 77 products |
| body firming lotion | 77 products |
| antiperspirant/deodorant | 73 products |
| around-eye cream | 68 products |
| mascara | 67 products |
| hair treatment/serum | 49 products |
| makeup primer | 48 products |
| facial powder | 48 products |
| hand cream | 45 products |
| anti-aging | 44 products |
| hair color and bleaching | 37 products |
| BB cream | 36 products |
| bath oil/salts/soak | 34 products |
| baby lotion | 34 products |
| liquid hand soap | 32 products |
| Tanning Sprays | 30 products |
| hair styling aide | 29 products |
| makeup remover | 25 products |
| makeup with SPF | 24 products |
| bar soap | 23 products |
| styling gel/lotion | 22 products |
| CC cream | 22 products |
| Facial Sun Care | 21 products |
| toners/astringents | 20 products |
| beard oil | 20 products |
| shaving cream | 18 products |
| baby soap | 17 products |
| fragrance for women | 16 products |
| baby oil | 16 products |
| diaper cream | 14 products |
| other eye makeup | 13 products |
| toothpaste | 12 products |
| sunless tanning | 12 products |
| baby shampoo | 11 products |
| vapor rubs | 10 products |
| fragrance for men | 10 products |
| lip plumper | 9 products |
| shaving cream (men's) | 8 products |
| foot moisturizer | 8 products |
| hair spray | 7 products |
| after shave | 7 products |
| bubble bath | 7 products |
| eye makeup remover | 7 products |
| detangler | 6 products |
| baby wipes | 5 products |
| after sun product | 4 products |
| cuticle treatment | 4 products |
| hand sanitizer | 4 products |
| oil controller | 4 products |
| antiperspirant/deodorant (men's) | 4 products |
| styling mousse/foam | 4 products |
| nail treatment | 3 products |
| body spray | 3 products |
| Lip Stain | 3 products |
| muscle/joint soreness | 3 products |
| other men's products | 3 products |
| baby bubble bath | 2 products |
| depilatory | 2 products |
| mouthwash | 2 products |
| polish remover | 1 products |
| Oils & Serums | 1 products |
| tanning oil | 1 products |
| skin fading/lightener | 1 products |
| baby powder | 1 products |
| foot odor control | 1 products |
| eyelash glue | 1 products |
| damaged skin treatment | 1 products |
| Under Eye Concealers | 1 products |
Contamination concerns
| Chemical |
|---|
| HYDROQUINONE |
Cancer
| Concern | Reference |
|---|---|
| One or more animal studies show tumor formation at high doses | Constantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97. |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments |
| 43489 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Ecotoxicology
| Concern | Reference |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
| Designated as safe for general or specific, limited use in food | FDA Everything Added to Food |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | Cosmetic Ingredient Review Assessments |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- Constantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
