Menu Close Menu

Menu

TOCOPHEROL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

Expand content Collapse content
lipstick1223 products
foundation1206 products
facial moisturizer/treatment721 products
lip balm709 products
moisturizer647 products
concealer571 products
recreational sunscreen537 products
lip gloss431 products
serums & essences413 products
eye shadow330 products
daily use with SPF278 products
bronzer/highlighter275 products
eye liner267 products
mask260 products
conditioner253 products
brow liner232 products
exfoliant/scrub230 products
shampoo223 products
facial cleanser221 products
antiperspirant/deodorant184 products
blush181 products
hair treatment/serum181 products
lip liner178 products
body oil175 products
mascara168 products
body wash/cleanser158 products
around-eye cream144 products
body firming lotion140 products
hand cream136 products
makeup primer118 products
baby sunscreen101 products
hair styling aide101 products
liquid hand soap95 products
lip balm with SPF92 products
bar soap85 products
hair color and bleaching78 products
facial powder78 products
anti-aging58 products
bath oil/salts/soak58 products
baby lotion58 products
lip plumper58 products
makeup remover58 products
toners/astringents49 products
beard oil49 products
BB cream45 products
fragrance for women44 products
CC cream44 products
43 products
styling gel/lotion39 products
baby soap32 products
shaving cream31 products
sunless tanning30 products
diaper cream29 products
hand sanitizer29 products
setting powder/spray29 products
bubble bath24 products
nail polish23 products
baby shampoo22 products
foot moisturizer21 products
hair spray21 products
antiperspirant/deodorant (men's)21 products
baby oil19 products
fragrance for men19 products
other eye makeup19 products
detangler17 products
beard care16 products
toothpaste14 products
cuticle treatment13 products
muscle/joint soreness13 products
body spray13 products
shaving cream (men's)12 products
styling mousse/foam12 products
baby wipes11 products
after sun product10 products
after shave10 products
nail treatment9 products
skin fading/lightener8 products
vapor rubs8 products
glitter8 products
beard cleanser8 products
eye makeup remover7 products
tanning oil7 products
mouthwash6 products
oil controller5 products
baby bubble bath5 products
depilatory5 products
polish remover5 products
foot cleansing3 products
body powder3 products
damaged skin treatment3 products
body art3 products
tooth whitening2 products
baby powder2 products
hair-loss treatment1 products
foot odor control1 products
eyelash glue1 products

Contamination concerns

Expand content Collapse content
Chemical
HYDROQUINONE

Cancer

Expand content Collapse content
Concern Reference
Subcutaneously injection of Vitamin E induced formation of fast growing fibrosarcomata at the site of the injectionConstantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.

Data gaps

Expand content Collapse content
Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
43489 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

Expand content Collapse content
Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

Expand content Collapse content
Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Constantinides P, Harkey M 1985. Initiation of a transplantable fibrosarcoma by the synergism of two non-initiators, alpha-tocopherol and soya oil. Virchows Arch A Pathol Anat Histopathol 405(3): 285-97.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer