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TITANIUM DIOXIDE

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate) and Occupational hazards (high)

Cancer

Cancer concern is MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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lipstick3398 products
foundation3377 products
eye shadow1935 products
concealer1528 products
lip gloss1223 products
bronzer/highlighter947 products
eye liner897 products
brow liner832 products
blush809 products
nail polish642 products
lip balm584 products
lip liner474 products
bar soap453 products
facial powder392 products
toothpaste316 products
mascara316 products
mask295 products
makeup primer216 products
facial moisturizer/treatment198 products
moisturizer169 products
shampoo157 products
hair color and bleaching132 products
exfoliant/scrub127 products
daily use with SPF114 products
BB cream113 products
body wash/cleanser110 products
facial cleanser109 products
around-eye cream108 products
lip plumper100 products
setting powder/spray99 products
CC cream95 products
91 products
serums & essences86 products
glitter68 products
bath oil/salts/soak49 products
hair styling aide45 products
shaving cream44 products
lip balm with SPF40 products
conditioner37 products
recreational sunscreen30 products
anti-aging27 products
hand cream26 products
sunless tanning23 products
styling gel/lotion22 products
tooth whitening21 products
body firming lotion19 products
body oil16 products
hair treatment/serum16 products
pore strips14 products
baby lotion13 products
nail treatment11 products
baby soap10 products
antiperspirant/deodorant8 products
skin fading/lightener8 products
shaving cream (men's)7 products
bubble bath7 products
liquid hand soap6 products
makeup remover6 products
toners/astringents6 products
hand sanitizer5 products
mouthwash4 products
oil controller4 products
body spray4 products
body art4 products
baby shampoo4 products
depilatory3 products
hair removal waxes3 products
hair spray3 products
baby toothpaste3 products
other eye makeup3 products
nail glue3 products
baby sunscreen3 products
damaged skin treatment3 products
after sun product2 products
foot moisturizer2 products
styling mousse/foam2 products
foot cleansing2 products
body powder1 products
eye makeup remover1 products
baby oil1 products
after shave1 products
cuticle treatment1 products
detangler1 products
hair relaxer1 products
muscle/joint soreness1 products
fragrance for men1 products
baby bubble bath1 products
beard care1 products

Occupational hazards

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Concern Reference
Allowed workplace exposures restricted to low dosesNational Library of Medicine HazMap

Cancer

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Concern Reference
Possible human carcinogenOpen scientific literature
Limited evidence of carcinogenicityNIOSH Occupational Carcinogens
Limited evidence of carcinogenicityInt'l Agency for Research on Cancer (IARC) - Carcinogens

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List

Decreased skin absorption

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Concern Reference
No absorption into intact skinOpen scientific literature

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmeticsFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Exempt from Batch Certification by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
21244 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Data Sources

  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Open scientific/peer reviewed literature
  • NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.

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