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Data: Good

Titanium Dioxide

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.

IMAGE SOURCE: PubChem

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Other Concerns

Non-reproductive organ system toxicity (moderate) and Occupational hazards (high)

SYNONYMS

1385RN 59, 1700 WHITE, 234DA, 500HD, 63B1 WHITE, A 200 (PIGMENT), A 330 (PIGMENT), A-FIL, A-FIL CREAM, A-FN 3, AEROLYST 7710, AEROSIL P 25, AEROSIL P 25S6, AEROSIL P 27, AEROSIL T 805, AI3-01334, AK 15 (PIGMENT), AMORPHOUS TITANIUM DIOXIDE, AMPERIT 780.0, AMT 100, AMT 600, ATLAS WHITE TITANIUM DIOXIDE, AUF 0015S, AUSTIOX R-CR 3, B 101 (PIGMENT), BAYER R-FD 1, BAYERTITAN A, BAYERTITAN AN 3, BAYERTITAN R-FD 1, BAYERTITAN R-FK 21, BAYERTITAN R-FK-D, BAYERTITAN R-KB 2, BAYERTITAN R-KB 3, BAYERTITAN R-KB 4, BAYERTITAN R-KB 5, BAYERTITAN R-KB 6, BAYERTITAN R-U 2, BAYERTITAN R-U-F, BAYERTITAN R-V-SE 20, BAYERTITAN T, BISTRATER L-NSC 200C, BLEND WHITE 9202, BR 29-7-2, BROOKITE, C 97 (OXIDE), C-WEISS 7, C.I. 77891, C.I. PIGMENT WHITE 6, CAB-O-TI, CALCOTONE WHITE T, CCRIS 590, CG-T, CI 77891, CI PIGMENT WHITE 6, CL 310, COSMETIC HYDROPHOBIC TIO2 9428, COSMETIC MICRO BLEND TIO2 9228, COSMETIC WHITE C47-5175, COSMETIC WHITE C47-9623, E 171, EINECS 236-675-5, FLAMENCO, HOMBITAN, HOMBITAN R 101D, HOMBITAN R 610K, HORSE HEAD A-410, HORSE HEAD A-420, HORSE HEAD R-710, HSDB 869, KH 360, KRONOS, KRONOS 2073, KRONOS CL 220, KRONOS RN 40P, KRONOS RN 56, KRONOS TITANIUM DIOXIDE, LEVANOX WHITE RKB, MICRO PARTICLE TITANIUM DIOXIDE, NCI-C04240, NCI-C0424O, NSC 15204, ORGASOL 1002D WHITE 10 EXTRA COS, P 25 (OXIDE), PIGMENT WHITE 6, R 680, RAYOX, RO 2, RUNA ARH 20, RUNA ARH 200, RUNA RH20, RUTIOX CR, TI-PURE, TI-PURE R 900, TI-PURE R 901, TICHLOR, TIN DIOXIDE DUST, TIO2, TIOFINE, TIONA T.D., TIONA TD, TIOXIDE, TIOXIDE A-DM, TIOXIDE AD-M, TIOXIDE R XL, TIOXIDE R-CR, TIOXIDE R-SM, TIOXIDE R.XL, TIOXIDE RHD, TIOXIDE RSM, TIPAQUE, TIPAQUE R 820, TITAFRANCE, TITAN WHITE, TITANDIOXID, TITANDIOXID (SWEDEN), TITANIA, TITANIC ANHYDRIDE, TITANIC OXIDE, TITANIUM DIOXIDE, TITANIUM DIOXIDE (NON-NANO), TITANIUM DIOXIDE SOL, TITANIUM DIOXIDE; TITANIUM DIOXIDE, TITANIUM OXIDE, TITANIUM OXIDE (TIO2), TITANIUM OXIDE (VAN), TITANIUM PEROXIDE, TITANIUM PEROXIDE (TIO2), TITANIUM WHITE, TITANIUM(IV) OXIDE, TITANOX, TITANOX 2010, TITANOX RANC, TRIOXIDE(S), TRONOX, UNITANE, UNITANE 0-110, UNITANE 0-220, UNITANE O-110, UNITANE O-220, UNITANE OR 450, UNITANE OR 650, UNITANE OR-150, UNITANE OR-340, UNITANE OR-342, UNITANE OR-350, UNITANE OR-540, UNITANE OR-640, UNIWHITE AO, UNIWHITE KO, UNIWHITE OR 450, UNIWHITE OR 650, ZOPAQUE, and ZOPAQUE LDC

Titanium dioxide is an inorganic compound used in a range of body care products such as sunscreens and makeup. It appears to have low skin penetration but inhalation is a concern.

Common concerns

See how this product scores for common concerns.

  • MODERATE
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reingredientive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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foundation3051 products
lipstick2546 products
eye shadow1854 products
concealer1284 products
lip gloss1080 products
bronzer/highlighter786 products
blush740 products
brow liner680 products
eye liner662 products
nail polish609 products
lip balm504 products
lip liner439 products
bar soap335 products
mask273 products
toothpaste270 products
facial powder266 products
facial moisturizer/treatment201 products
makeup primer194 products
mascara190 products
moisturizer141 products
setting powder/spray138 products
exfoliant/scrub129 products
daily use with SPF129 products
BB cream121 products
shampoo119 products
CC cream117 products
hair color and bleaching115 products
around-eye cream106 products
body wash/cleanser88 products
88 products
facial cleanser87 products
lip plumper87 products
serums & essences85 products
glitter64 products
bath oil/salts/soak54 products
lip balm with SPF43 products
shaving cream37 products
hair styling aide37 products
conditioner34 products
body oil33 products
recreational sunscreen31 products
anti-aging26 products
hand cream24 products
sunless tanning20 products
styling gel/lotion19 products
tooth whitening18 products
hair treatment/serum17 products
pore strips14 products
body firming lotion14 products
baby lotion14 products
nail treatment10 products
body powder9 products
baby soap9 products
skin fading/lightener9 products
shaving cream (men's)8 products
liquid hand soap8 products
bubble bath7 products
toners/astringents6 products
makeup remover5 products
hand sanitizer5 products
body spray5 products
mouthwash4 products
oil controller4 products
body art4 products
nail glue4 products
hair removal waxes3 products
baby toothpaste3 products
baby sunscreen3 products
damaged skin treatment3 products
baby shampoo3 products
depilatory2 products
antiperspirant/deodorant2 products
styling mousse/foam2 products
foot cleansing2 products
hair spray1 products
baby oil1 products
after sun product1 products
cuticle treatment1 products
detangler1 products
hair relaxer1 products
foot moisturizer1 products
muscle/joint soreness1 products
eyelash glue1 products
fragrance for men1 products
baby bubble bath1 products
beard care1 products

Occupational hazards

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CONCERN REFERENCE
Allowed workplace exposures restricted to low dosesNational Library of Medicine HazMap

Cancer

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CONCERN REFERENCE
Possible human carcinogenOpen scientific literature
Limited evidence of carcinogenicityNIOSH Occupational Carcinogens
Limited evidence of carcinogenicityInt'l Agency for Research on Cancer (IARC) - Carcinogens

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List

Decreased skin absorption

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CONCERN REFERENCE
No absorption into intact skinOpen scientific literature

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmeticsFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Exempt from Batch Certification by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
21244 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Open scientific/peer reviewed literature
  • NIOSH (National Institute for Occupational Safety and Health). 2006. NIOSH Carcinogens List (Potential occupational carcinogens). http://www.cdc.gov/niosh/npotocca.html.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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