EWG Skin Deep® | What is TETRASODIUM ETIDRONATE

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Data: Limited

Tetrasodium Etidronate

Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high) and Irritation (skin, eyes, or lungs) (low)

SYNONYMS

● (1-HYDROXYETHYLIDENE)BIS- TETRASODIUM SALT PHOSPHONIC ACID

● (1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID, TETRASODIUM SALT

● 1-DIPHOSPHONATE TETRASODIUM 1-HYDROXYETHANE-1

● 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID, TETRASODIUM SALT; PHOSPHONIC ACID, (1-HYDROXYETHYLIDENE)BIS-, TETRASODIUM SALT; TETRASODIUM 1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONATE; TETRASODIUM 1-HYDROXYETHYL

● PHOSPHONIC ACID, (1-HYDROXYETHYLIDENE)BIS-, TETRASODIUM SALT

● PHOSPHONIC ACID, (1HYDROXYETHYLIDENE)BIS, TETRASODIUM SALT

● TETRASODIUM (1-HYDROXYETHYLIDENE)BISPHOSPHONATE

● TETRASODIUM 1-HYDROXYETHANE-1, 1-DIPHOSPHONATE

● TETRASODIUM ETIDRONATE

● TETRASODIUM ETIDRONATE TETRASODIUM ETIDRONATE

● TETRASODIUM SALT (1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID

● TETRASODIUM SALT PHOSPHONIC ACID, (1-HYDROXYETHYLIDENE)BIS-

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation

Tetrasodium Etidronate is a diphosphonic acid derivative.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
HIGH

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

bar soap	211 products
exfoliant/scrub	21 products
facial cleanser	10 products
hair color and bleaching	8 products
body wash/cleanser	6 products
baby soap	5 products
conditioner	4 products
brow liner	2 products
shampoo	1 products
shaving cream (men's)	1 products
sunless tanning	1 products

Use restrictions

CONCERN	REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - any	Open scientific literature
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any	CosIng
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications	Cosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

CONCERN	REFERENCE
any irritation - weight of evidence unknown/unassessed	Open scientific literature

Data gaps

CONCERN	REFERENCE
0 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Persistence and bioaccumulation

CONCERN	REFERENCE
Not suspected to be persistent	Environment Canada Domestic Substance List
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

Open scientific/peer reviewed literature
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED^® mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability