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Data: Fair

Tetrasodium Edta

IMAGE SOURCE: PubChem

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Other Concerns

Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high)

SYNONYMS

● EDETATE SODIUM
● ETHYLENEDIAMINETETRAACETIC ACID TETRASODIUM SALT
● GLYCINE, N,N 1,2ETHANEDIYLBIS[N(CARBOXYMETHYL), TETRASODIUM SALT
● GLYCINE, N,N'-1,2-ETHANEDIYLBIS[N-(CARBOXYMETHYL)-, TETRASODIUM SALT
● N,N'-1,2-ETHANEDIYL BIS[N-(CARBOXYMETHYL)GLYCINE, TETRASODIUM SALT
● N,N'-1,2-ETHANEDIYLBIS[N-(CARBOXYMETHYL)- TETRASODIUM SALT GLYCINE
● N,N'-1,2-ETHANEDIYLBIS[N-(CARBOXYMETHYL)GLYCINE], TETRASODIUM SALT
● SODIUM EDETATE
● TETRASODIUM EDE TATE TETRAHYDRATE
● TETRASODIUM EDETATE
● TETRASODIUM EDETATE DIHYDRATE
● TETRASODIUM EDTA
● TETRASODIUM EDTA; TETRASODIUM ETHYLENEDIAMINETETRAACETATE
● TETRASODIUM ETHYLENE DIAMINE TETRAACETATE
● TETRASODIUM ETHYLENEDIAMINETETRAACETATE
● TETRASODIUM SALT GLYCINE, N,N'-1,2-ETHANEDIYLBIS[N-(CARBOXYMETHYL)-
● TETRASODIUM SALT N,N'-1,2-ETHANEDIYLBIS[N-(CARBOXYMETHYL)GLYCINE]

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


EDTA (ethylenediaminetetraacetic acid) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in a product.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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shampoo454 products
body wash/cleanser387 products
liquid hand soap265 products
conditioner215 products
hair color and bleaching193 products
bar soap188 products
foundation178 products
moisturizer121 products
facial cleanser91 products
exfoliant/scrub80 products
concealer77 products
styling gel/lotion61 products
mascara60 products
facial moisturizer/treatment59 products
hair treatment/serum54 products
hair styling aide50 products
antiperspirant/deodorant49 products
mask37 products
serums & essences31 products
hand cream28 products
bubble bath27 products
antiperspirant/deodorant (men's)24 products
baby soap20 products
blush19 products
baby shampoo18 products
eye liner18 products
toners/astringents17 products
daily use with SPF16 products
bronzer/highlighter15 products
styling mousse/foam15 products
facial powder15 products
body firming lotion15 products
bath oil/salts/soak12 products
around-eye cream11 products
makeup primer11 products
11 products
after sun product10 products
detangler10 products
hand sanitizer10 products
setting powder/spray10 products
baby wipes9 products
sunless tanning9 products
lipstick7 products
anti-aging6 products
hair spray6 products
brow liner6 products
BB cream6 products
makeup remover5 products
beard care5 products
beard cleanser5 products
baby bubble bath4 products
skin fading/lightener4 products
after shave4 products
recreational sunscreen4 products
baby lotion4 products
hair-loss treatment4 products
shaving cream (men's)3 products
nail treatment3 products
other eye makeup3 products
polish remover3 products
eyelash glue3 products
facial cleansing wipes3 products
foot moisturizer2 products
glitter2 products
shaving cream2 products
makeup removing wipes2 products
eye shadow1 products
fragrance for men1 products
muscle/joint soreness1 products
cuticle treatment1 products
lip balm1 products
mouthwash1 products
tooth whitening1 products
body powder1 products
lip gloss1 products
tanning oil1 products
body oil1 products
body cleansing wipes1 products
vapor rubs1 products
nail polish1 products

Enhanced skin absorption

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CONCERN REFERENCE
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Classified as any irritantOpen scientific literature

Occupational hazards

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CONCERN REFERENCE
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as medium human health priorityOpen scientific literature
Limited evidence of eye toxicityCPS&Q - Classification & Labelling
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Ecotoxicology

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CONCERN REFERENCE
Wildlife and environmental toxicityOpen scientific literature
Not suspected to be an environmental toxinOpen scientific literature

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
3889 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be bioaccumulativeOpen scientific literature
Not suspected to be persistentOpen scientific literature

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Open scientific/peer reviewed literature
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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