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SILICA, AMORPHOUS

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Persistence and bioaccumulation (high) and Non-reproductive organ system toxicity (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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lipstick1132 products
eye shadow751 products
foundation644 products
bronzer/highlighter415 products
concealer347 products
lip gloss259 products
blush220 products
moisturizer with SPF205 products
beach & sport sunscreen189 products
facial powder186 products
nail polish164 products
eye liner154 products
brow liner139 products
lip liner105 products
mascara85 products
makeup primer78 products
antiperspirant/deodorant74 products
serums & essences58 products
shampoo56 products
lip balm51 products
facial moisturizer/treatment51 products
exfoliant/scrub44 products
BB cream35 products
mask27 products
toothpaste22 products
hair color and bleaching21 products
lip balm with SPF18 products
antiperspirant/deodorant (men's)18 products
other eye makeup15 products
around-eye cream15 products
moisturizer13 products
facial cleanser12 products
lip plumper12 products
CC cream12 products
baby sunscreen11 products
pore strips8 products
depilatory7 products
anti-aging7 products
nail treatment6 products
body wash/cleanser6 products
hair styling aide6 products
makeup with SPF4 products
conditioner4 products
hair treatment/serum4 products
tooth whitening4 products
glitter4 products
mouthwash4 products
oil controller3 products
sunless tanning3 products
bath oil/salts/soak2 products
after sun product2 products
baby lotion2 products
body oil2 products
styling gel/lotion2 products
fragrance for men2 products
shaving cream2 products
fragrance for women2 products
toners/astringents1 products
after shave1 products
hair relaxer1 products
detangler1 products
damaged skin treatment1 products
diaper cream1 products
eyelash glue1 products
liquid hand soap1 products
beard oil1 products

Persistence and bioaccumulation

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Concern Reference
Persistent, bioaccumulative in wildlife and humansNational Library of Medicine HazMap
Persistent, bioaccumulative in wildlifeNational Library of Medicine HazMap
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of gastrointestinal or liver toxicityDossing, M and P. Skinhoj. Occupational Liver Injury. Present State of Knowledge and Future Perspectives. International Archives of Occupational and Environmental Health. 56:1-21. 1985. (Table 2: Chemically induced liver injury: morphologic features and examples of confirmed and suspected causative agents).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
65522 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Cancer

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Concern Reference
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsWorld Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 68;1997

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Dossing, M and P. Skinhoj. Occupational Liver Injury. Present State of Knowledge and Future Perspectives. International Archives of Occupational and Environmental Health. 56:1-21. 1985. (Table 2: Chemically induced liver injury: morphologic features and examples of confirmed and suspected causative agents).
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 68;1997
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.

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