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SILICA, AMORPHOUS

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms

Cancer

Cancer concern is LOW_MODERATE

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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lipstick1027 products
eye shadow624 products
foundation482 products
bronzer/highlighter341 products
concealer292 products
lip gloss235 products
moisturizer with SPF203 products
blush197 products
beach & sport sunscreen186 products
facial powder129 products
nail polish125 products
eye liner121 products
brow liner113 products
lip liner87 products
makeup primer61 products
mascara53 products
serums & essences52 products
antiperspirant/deodorant46 products
lip balm46 products
facial moisturizer/treatment35 products
shampoo32 products
exfoliant/scrub30 products
BB cream23 products
other eye makeup22 products
toothpaste20 products
mask19 products
lip balm with SPF18 products
around-eye cream15 products
baby sunscreen14 products
CC cream12 products
lip plumper12 products
hair color and bleaching11 products
facial cleanser10 products
moisturizer7 products
baby toothpaste6 products
anti-aging5 products
hair styling aide5 products
glitter5 products
mouthwash4 products
body wash/cleanser4 products
tooth whitening3 products
antiperspirant/deodorant (men's)3 products
makeup with SPF3 products
oil controller3 products
body oil3 products
nail treatment3 products
hair treatment/serum3 products
bath oil/salts/soak2 products
depilatory2 products
fragrance for men2 products
fragrance for women2 products
styling gel/lotion2 products
diaper cream1 products
toners/astringents1 products
after sun product1 products
sunless tanning1 products
conditioner1 products
vapor rubs1 products
beard oil1 products
shaving cream1 products
body powder1 products
eyelash glue1 products
baby lotion1 products

Persistence and bioaccumulation

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Concern Reference
Persistent, bioaccumulative in wildlife and humansNational Library of Medicine HazMap
Persistent, bioaccumulative in wildlifeNational Library of Medicine HazMap
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Cancer

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Concern Reference
Limited evidence of carcinogenicityNIOSH Occupational Carcinogens, Centers for Disease Control and Prevention (CDC)
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsWorld Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 68;1997

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of gastrointestinal or liver toxicityDossing, M and P. Skinhoj. Occupational Liver Injury. Present State of Knowledge and Future Perspectives. International Archives of Occupational and Environmental Health. 56:1-21. 1985. (Table 2: Chemically induced liver injury: morphologic features and examples of confirmed and suspected causative agents).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
65522 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NIOSH Occupational Carcinogens, Centers for Disease Control and Prevention (CDC)
  • World Health Organization, International Agency for Research on Cancer IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans. Lists of Group 1, 2a, and 2b substances can be obtained. http://monographs.iarc.fr/ENG/Classification/index.php; Vol 68;1997
  • Dossing, M and P. Skinhoj. Occupational Liver Injury. Present State of Knowledge and Future Perspectives. International Archives of Occupational and Environmental Health. 56:1-21. 1985. (Table 2: Chemically induced liver injury: morphologic features and examples of confirmed and suspected causative agents).
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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