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SD ALCOHOL 40B
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Enhanced skin absorption, Non-reproductive organ system toxicity (low), and Multiple, additive exposure sources (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| beach & sport sunscreen | 50 products |
| shampoo | 21 products |
| hair spray | 19 products |
| mask | 9 products |
| moisturizer with SPF | 8 products |
| hair color and bleaching | 7 products |
| fragrance for women | 6 products |
| serums & essences | 3 products |
| foundation | 3 products |
| facial moisturizer/treatment | 3 products |
| body wash/cleanser | 2 products |
| body spray | 2 products |
| after shave | 2 products |
| makeup primer | 2 products |
| makeup with SPF | 2 products |
| after sun product | 2 products |
| toners/astringents | 2 products |
| body firming lotion | 2 products |
| antiperspirant/deodorant | 2 products |
| hair treatment/serum | 2 products |
| hair styling aide | 1 products |
| oil controller | 1 products |
| baby sunscreen | 1 products |
| exfoliant/scrub | 1 products |
| foot odor control | 1 products |
| mascara | 1 products |
| fragrance for men | 1 products |
| moisturizer | 1 products |
| hand sanitizer | 1 products |
Enhanced skin absorption
| Concern | Reference |
|---|---|
| Penetration enhancer | Cosmetic Ingredient Review Assessments |
| Ethanol has been found to act as a penetration enhancer for many chemicals. | Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5. |
Developmental/reproductive toxicity
| Concern | Reference |
|---|---|
| Limited evidence of reproductive toxicity | National Library of Medicine HazMap |
| Limited evidence of reproductive toxicity | Frazier , L and M. L. Hage (eds.). Reproductive Hazards of the Workplace, Wiley Europe, 1998. Table 10 (Partial List of Reproductive Toxicants) available at http://www.pharmacy.ohio-state.edu/homepage/safety/chemhygiene_table_repro.pdf. |
Multiple, additive exposure sources
| Concern | Reference |
|---|---|
| Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
Cancer
| Concern | Reference |
|---|---|
| Cancer - limited evidence | A Relational Database of Hazardous Chemicals and Occupational Diseases Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html; National Toxicology Program. 10th Report on Carcinogens (2002). http://ehis.niehs.nih.gov/roc/toc10.html |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Limited evidence of gastrointestinal or liver toxicity | National Library of Medicine HazMap |
| Limited evidence of sense organ toxicity | Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria). |
| reproductive - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Data gaps
| Concern | Reference |
|---|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product | Cosmetic Ingredient Review Assessments |
| 1 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Miscellaneous
| Concern | Reference |
|---|---|
| Occupational hazards related to handling | CPS&Q - Classification & Labelling |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any | Cosmetic Ingredient Review Assessments |
Neurotoxicity
| Concern | Reference |
|---|---|
| nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox study | National Library of Medicine HazMap |
Data Sources
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- Frazier , L and M. L. Hage (eds.). Reproductive Hazards of the Workplace, Wiley Europe, 1998. Table 10 (Partial List of Reproductive Toxicants) available at http://www.pharmacy.ohio-state.edu/homepage/safety/chemhygiene_table_repro.pdf.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- A Relational Database of Hazardous Chemicals and Occupational Diseases Browse Haz-Map by Adverse Effects http://hazmap.nlm.nih.gov/hazmapadv.html; National Toxicology Program. 10th Report on Carcinogens (2002). http://ehis.niehs.nih.gov/roc/toc10.html
- Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
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