EWG Skin Deep® | What is PYRIDOXINE HCL

HOW WE DETERMINE SCORES Learn more About EWG VERIFIED™

Data: Fair

Pyridoxine Hcl

IMAGE SOURCE: PubChem

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Other Concerns

SYNONYMS

● 3,4-PYRIDINEDIMETHANOL, 5-HYDROXY-6-METHYL-, HYDROCHLORIDE

● 3,4PYRIDINEDIMETHANOL, 5HYDROXY6METHYL, HYDROCHLORIDE

● 5-HYDROXY-6-METHYL- HYDROCHLORIDE 3,4-PYRIDINEDIMETHANOL

● 5-HYDROXY-6-METHYL-3,4-PYRIDINEDIMETHANOL HYDROCHLORIDE

● ADEROMINE HYDROCHLORIDE

● ADEROXINE

● HYDROCHLORIDE 3,4-PYRIDINEDIMETHANOL, 5-HYDROXY-6-METHYL-

● PYRIDOXINE HCL

● PYRIDOXINE HYDROCHLORIDE

● VITAMIN B6 HYDROCHLORIDE

This ingredient is not currently on EWG's Skin Deep Restricted or Unacceptable Lists.

Pyridoxine HCl is a substituted aromatic compound.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
LOW

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

shampoo	23 products
conditioner	22 products
facial moisturizer/treatment	19 products
serums & essences	10 products
hair treatment/serum	10 products
mask	6 products
recreational sunscreen	5 products
hair styling aide	5 products
hair color and bleaching	4 products
toners/astringents	3 products
hair spray	2 products
daily use with SPF	2 products
exfoliant/scrub	2 products
baby sunscreen	1 products
after shave	1 products
facial cleanser	1 products
skin fading/lightener	1 products
anti-aging	1 products
styling gel/lotion	1 products
after sun product	1 products
sunless tanning	1 products
moisturizer	1 products
other eye makeup	1 products

Multiple, additive exposure sources

CONCERN	REFERENCE
Designated as safe for general or specific, limited use in food	FDA Everything Added to Food
Designated as safe for general or specific, limited use in food	FDA Food Additive Status

Data gaps

CONCERN	REFERENCE
6966 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Persistence and bioaccumulation

CONCERN	REFERENCE
Not suspected to be persistent	Environment Canada Domestic Substance List
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability