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PROPYLPARABEN

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Endocrine disruption (high), and Ecotoxicology (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is MODERATE

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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foundation248 products
mascara141 products
lipstick138 products
moisturizer137 products
eye liner134 products
eye shadow126 products
brow liner113 products
concealer105 products
facial powder100 products
lip gloss100 products
bronzer/highlighter61 products
blush61 products
facial moisturizer/treatment48 products
facial cleanser48 products
lip liner46 products
conditioner38 products
hair styling aide33 products
styling gel/lotion27 products
daily use with SPF26 products
mask24 products
anti-aging22 products
body firming lotion22 products
hair treatment/serum20 products
lip balm18 products
hand cream17 products
mouthwash17 products
recreational sunscreen16 products
foot moisturizer15 products
setting powder/spray15 products
sunless tanning14 products
makeup primer14 products
around-eye cream13 products
hair color and bleaching13 products
toners/astringents12 products
shaving cream12 products
after sun product11 products
nail polish10 products
exfoliant/scrub9 products
shampoo8 products
skin fading/lightener7 products
makeup remover7 products
lip balm with SPF6 products
body wash/cleanser5 products
styling mousse/foam5 products
hair-loss treatment5 products
cuticle treatment5 products
BB cream5 products
baby sunscreen5 products
damaged skin treatment5 products
eye makeup remover4 products
baby lotion4 products
nail treatment4 products
hand sanitizer4 products
4 products
after shave3 products
diaper cream3 products
detangler3 products
serums & essences3 products
glitter3 products
toothpaste2 products
fragrance for women2 products
muscle/joint soreness2 products
foot odor control2 products
liquid hand soap2 products
beard care2 products
hair spray1 products
tooth whitening1 products
bath oil/salts/soak1 products
hair removal waxes1 products
oil controller1 products
lip plumper1 products
shaving cream (men's)1 products
foot cleansing1 products
body oil1 products
hair relaxer1 products
other eye makeup1 products
bar soap1 products
body powder1 products
polish remover1 products

Endocrine disruption

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Concern Reference
Known human any disruptorOpen scientific literature
Human endocrine disruptor - strong evidenceEuropean Commission on Endocrine Disruption
One or more studies show significant wildlife and the environment disruptionEuropean Commission on Endocrine Disruption
Limited evidence of endocrine disruptionOpen scientific literature
Limited evidence of any disruptionOpen scientific literature
One or more studies show weak endocrine disruptionEWG Assessment of Open Scientific Literature
One or more studies show weak endocrine disruptionOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Human immune toxicant or allergen - strong evidenceOpen scientific literature
Human immune toxicant or allergen - moderate evidenceOpen scientific literature
One or more human case studies show possible immune or allergenic effectsOpen scientific literature

Developmental/reproductive toxicity

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Concern Reference
Possible human reproductive or developmental toxinOpen scientific literature
One or more animal studies show any effects at low dosesOpen scientific literature

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyOpen scientific literature
Determined safe for use in cosmetics, subject to concentration or use limitations - anyOpen scientific literature
Determined safe for use in cosmetics, subject to concentration or use limitations - anyCosmetic Ingredient Review Assessments

Ecotoxicology

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Concern Reference
Wildlife and environmental toxicityOpen scientific literature
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
903 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
Not suspected to be persistentEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data Sources

  • Open scientific/peer reviewed literature
  • EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
  • EWG Assessment of Open Scientific Literature
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

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