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Data: Fair

Propylene Glycol

IMAGE SOURCE: PubChem

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Other Concerns

Enhanced skin absorption, Use restrictions (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (high)

SYNONYMS

1,2-DIHYDROXYPROPANE, 1,2-PROPANEDIOL, 2-HYDROXYPROPANOL, METHYLETHYL GLYCOL, PROPANE-1,2-DIOL, and PROPYLENE GLYCOL

Propylene glycol is a small organic alcohol commonly used as a skin conditioning agent. It has been associated with irritant and allergic contact dermatitis as well as contact urticaria in humans; these sensitization effects can be manifested at propylene glycol concentrations as low as 2%.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • MODERATE
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reingredientive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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shampoo328 products
conditioner291 products
foundation264 products
hair color and bleaching256 products
concealer250 products
antiperspirant/deodorant241 products
mask221 products
moisturizer195 products
facial moisturizer/treatment186 products
hair styling aide185 products
mascara181 products
body wash/cleanser178 products
hair treatment/serum168 products
lip balm159 products
facial cleanser130 products
serums & essences125 products
styling gel/lotion124 products
hand sanitizer120 products
antiperspirant/deodorant (men's)111 products
liquid hand soap108 products
recreational sunscreen100 products
body spray97 products
bar soap96 products
exfoliant/scrub95 products
mouthwash92 products
eye liner78 products
makeup primer70 products
sunless tanning69 products
brow liner66 products
daily use with SPF61 products
fragrance for women57 products
setting powder/spray57 products
eye shadow56 products
eyelash glue51 products
hair spray44 products
BB cream41 products
makeup remover40 products
toothpaste39 products
body firming lotion38 products
styling mousse/foam36 products
hair-loss treatment36 products
shaving cream35 products
lip gloss34 products
hand cream34 products
toners/astringents33 products
around-eye cream30 products
lipstick28 products
fragrance for men27 products
polish remover27 products
foot moisturizer26 products
detangler25 products
bronzer/highlighter23 products
after sun product22 products
anti-aging21 products
after shave21 products
baby wipes21 products
baby sunscreen20 products
CC cream18 products
blush17 products
nail treatment16 products
bubble bath14 products
foot cleansing14 products
glitter14 products
skin fading/lightener10 products
tooth whitening10 products
bath oil/salts/soak10 products
nail polish9 products
hair relaxer9 products
9 products
baby lotion8 products
body oil8 products
muscle/joint soreness7 products
lip balm with SPF6 products
shaving cream (men's)5 products
eye makeup remover5 products
baby toothpaste5 products
pore strips5 products
damaged skin treatment4 products
beard care4 products
foot odor control3 products
depilatory2 products
diaper cream2 products
baby soap2 products
baby shampoo2 products
baby oil2 products
cuticle treatment1 products
lip plumper1 products
tanning oil1 products
other eye makeup1 products
nail glue1 products
beard cleanser1 products
other men's products1 products

Enhanced skin absorption

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CONCERN REFERENCE
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Classified as skin irritantNational Library of Medicine HazMap

Allergies/immunotoxicity

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CONCERN REFERENCE
Limited evidence of skin and immune system toxicity or allergiesOpen scientific literature

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Use restrictions

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CONCERN REFERENCE
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Data gaps

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CONCERN REFERENCE
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
5589 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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CONCERN REFERENCE
Not likely to be a any toxicant in humansNTP - Risks to Human Reproduction

Multiple, additive exposure sources

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CONCERN REFERENCE
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • NTP (National Toxicology Program). 2006. NTP Center for the Evaluation fo Risks to Human Reproduction (CERHR). NTP-CERHR Reports and Monographs.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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