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PROPYLENE GLYCOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Use restrictions (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation182 products
shampoo119 products
hair color and bleaching116 products
concealer110 products
mask83 products
beach & sport sunscreen77 products
conditioner75 products
mascara64 products
body wash/cleanser57 products
facial moisturizer/treatment55 products
moisturizer54 products
serums & essences51 products
lip balm46 products
antiperspirant/deodorant44 products
moisturizer with SPF43 products
facial cleanser40 products
styling gel/lotion36 products
hair styling aide34 products
mouthwash29 products
eye liner27 products
lipstick27 products
hair treatment/serum25 products
liquid hand soap24 products
makeup primer22 products
makeup remover21 products
body spray20 products
lip gloss19 products
antiperspirant/deodorant (men's)19 products
exfoliant/scrub19 products
eyelash glue18 products
bar soap17 products
brow liner16 products
body firming lotion16 products
around-eye cream16 products
toners/astringents15 products
bronzer/highlighter14 products
detangler14 products
styling mousse/foam13 products
hand sanitizer13 products
fragrance for women13 products
shaving cream12 products
fragrance for men11 products
foot moisturizer11 products
hair spray11 products
toothpaste9 products
sunless tanning9 products
BB cream9 products
eye shadow9 products
CC cream9 products
bath oil/salts/soak8 products
baby wipes7 products
anti-aging6 products
lip balm with SPF6 products
after sun product5 products
hair relaxer5 products
polish remover5 products
tooth whitening5 products
after shave4 products
nail treatment4 products
shaving cream (men's)3 products
other eye makeup3 products
hand cream3 products
bubble bath3 products
foot cleansing3 products
baby sunscreen3 products
facial powder2 products
eye makeup remover2 products
baby bubble bath2 products
baby soap1 products
baby toothpaste1 products
body oil1 products
glitter1 products
nail glue1 products
vapor rubs1 products
baby lotion1 products
makeup with SPF1 products
depilatory1 products
lip plumper1 products
body powder1 products
baby oil1 products
damaged skin treatment1 products
pore strips1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as skin irritantNational Library of Medicine HazMap

Allergies/immunotoxicity

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Concern Reference
Propylene glycol was found to provoke allergic reactions in patients with eczema and other skin allergies.CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Data gaps

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Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
5589 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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Concern Reference
Not likely to be a any toxicant in humansNTP 2005 (Jahnke et al)

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • NTP 2005 (Jahnke et al)
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

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