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PROPYLENE GLYCOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Use restrictions (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation264 products
concealer162 products
shampoo143 products
hair color and bleaching133 products
mascara112 products
conditioner99 products
mask91 products
body wash/cleanser90 products
facial moisturizer/treatment84 products
beach & sport sunscreen77 products
serums & essences70 products
eye liner70 products
moisturizer63 products
hair styling aide53 products
antiperspirant/deodorant50 products
lip balm47 products
moisturizer with SPF45 products
liquid hand soap45 products
facial cleanser44 products
styling gel/lotion41 products
makeup primer40 products
eye shadow36 products
hair treatment/serum36 products
mouthwash35 products
body spray29 products
antiperspirant/deodorant (men's)28 products
hand sanitizer28 products
lipstick27 products
brow liner25 products
bar soap25 products
makeup remover24 products
exfoliant/scrub23 products
bronzer/highlighter21 products
body firming lotion19 products
fragrance for women18 products
fragrance for men18 products
eyelash glue18 products
hair spray17 products
detangler17 products
styling mousse/foam16 products
toners/astringents16 products
lip gloss15 products
shaving cream14 products
around-eye cream14 products
sunless tanning12 products
foot moisturizer12 products
toothpaste12 products
BB cream12 products
CC cream10 products
anti-aging8 products
bath oil/salts/soak8 products
nail treatment7 products
hair relaxer7 products
baby wipes7 products
after shave6 products
polish remover6 products
lip balm with SPF6 products
tooth whitening5 products
after sun product5 products
hand cream5 products
foot cleansing4 products
shaving cream (men's)4 products
bubble bath3 products
other eye makeup3 products
baby sunscreen3 products
eye makeup remover3 products
blush3 products
3 products
hair-loss treatment2 products
baby lotion2 products
baby bubble bath2 products
diaper cream2 products
facial powder2 products
pore strips2 products
depilatory1 products
foot odor control1 products
lip plumper1 products
body oil1 products
baby soap1 products
vapor rubs1 products
baby oil1 products
beard care1 products
oil controller1 products
tanning oil1 products
makeup with SPF1 products
glitter1 products
baby toothpaste1 products
nail glue1 products
body powder1 products
damaged skin treatment1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as skin irritantNational Library of Medicine HazMap

Allergies/immunotoxicity

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Concern Reference
Propylene glycol was found to provoke allergic reactions in patients with eczema and other skin allergies.CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Data gaps

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Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
5589 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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Concern Reference
Not likely to be a any toxicant in humansNTP 2005 (Jahnke et al)

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • NTP 2005 (Jahnke et al)
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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