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PROPYLENE GLYCOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Use restrictions (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation382 products
shampoo354 products
conditioner306 products
concealer302 products
hair color and bleaching248 products
antiperspirant/deodorant243 products
mask234 products
mascara218 products
moisturizer208 products
hair styling aide198 products
body wash/cleanser197 products
facial moisturizer/treatment194 products
lip balm162 products
hair treatment/serum155 products
facial cleanser150 products
antiperspirant/deodorant (men's)136 products
bar soap135 products
styling gel/lotion133 products
serums & essences126 products
hand sanitizer119 products
body spray109 products
liquid hand soap106 products
eye liner100 products
recreational sunscreen99 products
mouthwash94 products
exfoliant/scrub89 products
brow liner75 products
makeup primer73 products
sunless tanning70 products
fragrance for women62 products
daily use with SPF61 products
setting powder/spray61 products
eye shadow56 products
eyelash glue50 products
hair spray47 products
makeup remover42 products
toothpaste40 products
shaving cream38 products
styling mousse/foam38 products
toners/astringents38 products
hair-loss treatment38 products
body firming lotion37 products
BB cream36 products
around-eye cream35 products
lipstick34 products
hand cream33 products
fragrance for men28 products
polish remover28 products
foot moisturizer26 products
anti-aging25 products
lip gloss25 products
detangler25 products
bronzer/highlighter25 products
CC cream24 products
after sun product22 products
baby wipes21 products
after shave20 products
baby sunscreen20 products
nail treatment15 products
bubble bath14 products
tooth whitening13 products
foot cleansing13 products
blush13 products
glitter13 products
bath oil/salts/soak11 products
nail polish11 products
skin fading/lightener10 products
hair relaxer10 products
10 products
body oil9 products
baby lotion8 products
muscle/joint soreness6 products
lip balm with SPF6 products
shaving cream (men's)5 products
eye makeup remover5 products
baby toothpaste5 products
pore strips5 products
other eye makeup4 products
damaged skin treatment4 products
beard care4 products
depilatory3 products
foot odor control3 products
cuticle treatment3 products
diaper cream2 products
baby soap2 products
baby shampoo2 products
baby oil2 products
lip plumper1 products
tanning oil1 products
facial powder1 products
nail glue1 products
beard cleanser1 products
other men's products1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as skin irritantNational Library of Medicine HazMap

Allergies/immunotoxicity

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Concern Reference
Limited evidence of skin and immune system toxicity or allergiesOpen scientific literature

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Data gaps

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Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
5589 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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Concern Reference
Not likely to be a any toxicant in humansNTP - Risks to Human Reproduction

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • NTP (National Toxicology Program). 2006. NTP Center for the Evaluation fo Risks to Human Reproduction (CERHR). NTP-CERHR Reports and Monographs.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

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