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PROPYLENE GLYCOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Use restrictions (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation293 products
shampoo211 products
concealer165 products
conditioner149 products
hair color and bleaching141 products
body wash/cleanser123 products
mascara114 products
mask112 products
hair styling aide108 products
facial moisturizer/treatment98 products
moisturizer98 products
beach & sport sunscreen91 products
serums & essences81 products
antiperspirant/deodorant75 products
mouthwash68 products
eye liner68 products
facial cleanser64 products
hair treatment/serum61 products
styling gel/lotion58 products
lip balm58 products
antiperspirant/deodorant (men's)56 products
moisturizer with SPF54 products
makeup primer53 products
exfoliant/scrub43 products
bar soap42 products
body firming lotion41 products
liquid hand soap40 products
toothpaste39 products
eye shadow36 products
hair spray32 products
makeup remover31 products
hand sanitizer31 products
lipstick27 products
setting powder/spray26 products
brow liner25 products
sunless tanning23 products
body spray23 products
styling mousse/foam22 products
bronzer/highlighter22 products
shaving cream21 products
detangler20 products
toners/astringents19 products
around-eye cream19 products
BB cream18 products
eyelash glue18 products
fragrance for women17 products
fragrance for men17 products
foot moisturizer15 products
lip gloss15 products
after sun product13 products
anti-aging12 products
hand cream10 products
bath oil/salts/soak10 products
polish remover10 products
hair relaxer10 products
CC cream10 products
after shave7 products
tooth whitening7 products
baby wipes7 products
nail treatment6 products
foot cleansing6 products
lip balm with SPF6 products
baby sunscreen5 products
5 products
shaving cream (men's)4 products
bubble bath4 products
eye makeup remover4 products
blush3 products
other eye makeup3 products
hair-loss treatment2 products
baby lotion2 products
diaper cream2 products
facial powder2 products
baby soap2 products
baby toothpaste2 products
baby shampoo2 products
pore strips2 products
beard care2 products
depilatory1 products
foot odor control1 products
lip plumper1 products
oil controller1 products
baby bubble bath1 products
tanning oil1 products
body oil1 products
glitter1 products
vapor rubs1 products
nail glue1 products
body powder1 products
baby oil1 products
damaged skin treatment1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as skin irritantNational Library of Medicine HazMap

Allergies/immunotoxicity

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Concern Reference
Propylene glycol was found to provoke allergic reactions in patients with eczema and other skin allergies.CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Data gaps

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Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
5589 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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Concern Reference
Not likely to be a any toxicant in humansNTP 2005 (Jahnke et al)

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • NTP 2005 (Jahnke et al)
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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