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PROPYLENE GLYCOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Use restrictions (low), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation152 products
beach & sport sunscreen91 products
concealer77 products
hair color and bleaching59 products
shampoo51 products
moisturizer with SPF45 products
serums & essences40 products
conditioner38 products
mascara33 products
mask33 products
moisturizer32 products
facial cleanser32 products
facial moisturizer/treatment31 products
body wash/cleanser26 products
lipstick25 products
antiperspirant/deodorant21 products
lip balm19 products
lip gloss19 products
styling gel/lotion17 products
eye liner16 products
around-eye cream15 products
makeup remover13 products
liquid hand soap12 products
bronzer/highlighter12 products
bar soap12 products
body spray10 products
hair styling aide10 products
brow liner9 products
CC cream9 products
makeup primer8 products
eye shadow8 products
mouthwash7 products
detangler7 products
styling mousse/foam6 products
toners/astringents6 products
exfoliant/scrub6 products
hair spray6 products
fragrance for women6 products
bath oil/salts/soak6 products
lip balm with SPF6 products
antiperspirant/deodorant (men's)5 products
baby sunscreen5 products
hair treatment/serum5 products
shaving cream4 products
baby wipes3 products
sunless tanning3 products
fragrance for men3 products
other eye makeup3 products
BB cream3 products
anti-aging3 products
foot moisturizer3 products
after shave2 products
hair relaxer2 products
polish remover2 products
hand sanitizer2 products
facial powder2 products
baby bubble bath2 products
shaving cream (men's)1 products
toothpaste1 products
after sun product1 products
baby soap1 products
body firming lotion1 products
baby toothpaste1 products
body oil1 products
eyelash glue1 products
vapor rubs1 products
baby lotion1 products
tooth whitening1 products
hand cream1 products
nail treatment1 products
body powder1 products
eye makeup remover1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerCosmetic Ingredient Review Assessments

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as skin irritantNational Library of Medicine HazMap

Allergies/immunotoxicity

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Concern Reference
Limited evidence of skin and immune system toxicity or allergiesCIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List

Use restrictions

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Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Data gaps

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Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
5589 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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Concern Reference
Not likely to be a any toxicant in humansNTP 2005 (Jahnke et al)

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Determined safe for use in cosmetics up to a specified concentration limitCosmetic Ingredient Review Assessments

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
  • CIR (Cosmetic Ingredient Review) 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • NTP 2005 (Jahnke et al)
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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