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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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foundation605 products
shampoo378 products
facial moisturizer/treatment333 products
conditioner311 products
moisturizer311 products
concealer264 products
facial cleanser240 products
body wash/cleanser236 products
serums & essences202 products
mask199 products
liquid hand soap187 products
mascara184 products
eye shadow149 products
daily use with SPF144 products
hair treatment/serum126 products
exfoliant/scrub113 products
toners/astringents103 products
around-eye cream102 products
blush95 products
body firming lotion94 products
bronzer/highlighter87 products
hair styling aide84 products
makeup primer77 products
makeup remover69 products
eye liner65 products
hand cream64 products
recreational sunscreen61 products
lipstick59 products
facial powder45 products
styling gel/lotion43 products
hair color and bleaching43 products
setting powder/spray43 products
anti-aging42 products
toothpaste41 products
bubble bath40 products
lip gloss38 products
baby wipes34 products
sunless tanning33 products
brow liner33 products
32 products
baby shampoo31 products
antiperspirant/deodorant31 products
mouthwash30 products
detangler29 products
body spray28 products
shaving cream26 products
baby soap24 products
CC cream23 products
hand sanitizer21 products
BB cream18 products
hair spray17 products
baby lotion16 products
lip balm16 products
bath oil/salts/soak15 products
after sun product14 products
after shave14 products
beard care13 products
foot moisturizer12 products
baby toothpaste12 products
baby bubble bath11 products
bar soap11 products
eye makeup remover11 products
glitter9 products
styling mousse/foam8 products
shaving cream (men's)8 products
baby sunscreen8 products
lip liner6 products
beard cleanser5 products
skin fading/lightener4 products
nail polish4 products
fragrance for women4 products
body oil4 products
oil controller4 products
antiperspirant/deodorant (men's)4 products
hair-loss treatment3 products
nail treatment3 products
other eye makeup3 products
damaged skin treatment3 products
foot odor control3 products
muscle/joint soreness2 products
diaper cream2 products
depilatory2 products
hair relaxer2 products
polish remover2 products
lip balm with SPF2 products
cuticle treatment1 products
lip plumper1 products
foot cleansing1 products
baby oil1 products
pore strips1 products
tanning oil1 products
eyelash glue1 products


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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
356 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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