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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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foundation535 products
moisturizer240 products
shampoo229 products
facial moisturizer/treatment210 products
concealer208 products
conditioner170 products
body wash/cleanser169 products
facial cleanser145 products
serums & essences115 products
mascara113 products
mask108 products
eye shadow96 products
liquid hand soap92 products
moisturizer with SPF80 products
exfoliant/scrub70 products
around-eye cream67 products
blush65 products
bronzer/highlighter60 products
toners/astringents54 products
makeup primer52 products
eye liner45 products
hair treatment/serum45 products
beach & sport sunscreen44 products
makeup remover44 products
hair styling aide44 products
facial powder38 products
lip gloss38 products
styling gel/lotion37 products
hair color and bleaching37 products
hand cream33 products
body firming lotion33 products
baby wipes32 products
baby shampoo30 products
lipstick27 products
toothpaste25 products
baby soap24 products
anti-aging20 products
bubble bath20 products
antiperspirant/deodorant19 products
baby lotion18 products
shaving cream18 products
18 products
brow liner16 products
CC cream16 products
detangler15 products
sunless tanning15 products
hair spray13 products
baby bubble bath13 products
lip balm12 products
mouthwash11 products
hand sanitizer11 products
glitter9 products
after shave9 products
beard care9 products
BB cream8 products
after sun product8 products
foot moisturizer7 products
bar soap7 products
shaving cream (men's)7 products
eye makeup remover7 products
bath oil/salts/soak6 products
nail treatment6 products
lip liner6 products
body spray5 products
baby toothpaste5 products
oil controller5 products
antiperspirant/deodorant (men's)5 products
styling mousse/foam4 products
lip balm with SPF2 products
diaper cream2 products
beard cleanser2 products
nail polish2 products
other eye makeup2 products
damaged skin treatment2 products
body oil1 products
hair relaxer1 products
foot cleansing1 products
muscle/joint soreness1 products
hair-loss treatment1 products
cuticle treatment1 products
depilatory1 products
lip plumper1 products
baby oil1 products
baby sunscreen1 products
polish remover1 products
tanning oil1 products


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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
356 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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