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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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foundation636 products
shampoo411 products
facial moisturizer/treatment366 products
moisturizer337 products
conditioner335 products
concealer291 products
facial cleanser256 products
body wash/cleanser239 products
mascara206 products
liquid hand soap205 products
mask196 products
serums & essences187 products
eye shadow153 products
hair treatment/serum146 products
daily use with SPF146 products
toners/astringents113 products
body firming lotion111 products
hair styling aide107 products
around-eye cream106 products
exfoliant/scrub100 products
blush95 products
bronzer/highlighter84 products
eye liner80 products
makeup primer79 products
makeup remover76 products
hand cream68 products
hair color and bleaching66 products
recreational sunscreen66 products
lipstick59 products
styling gel/lotion51 products
toothpaste48 products
setting powder/spray48 products
facial powder47 products
anti-aging45 products
bubble bath42 products
lip gloss38 products
sunless tanning37 products
brow liner37 products
BB cream35 products
35 products
mouthwash30 products
baby shampoo30 products
baby wipes30 products
CC cream29 products
antiperspirant/deodorant28 products
detangler27 products
shaving cream27 products
body spray26 products
baby soap23 products
hair spray21 products
hand sanitizer20 products
lip balm16 products
after sun product15 products
beard care15 products
foot moisturizer14 products
styling mousse/foam14 products
baby lotion14 products
after shave14 products
bar soap12 products
baby toothpaste12 products
eye makeup remover12 products
bath oil/salts/soak11 products
baby bubble bath11 products
glitter10 products
baby sunscreen8 products
shaving cream (men's)6 products
lip liner6 products
antiperspirant/deodorant (men's)5 products
beard cleanser5 products
skin fading/lightener4 products
fragrance for women4 products
body oil4 products
oil controller4 products
muscle/joint soreness3 products
depilatory3 products
damaged skin treatment3 products
foot odor control3 products
polish remover3 products
diaper cream2 products
hair-loss treatment2 products
nail treatment2 products
nail polish2 products
other eye makeup2 products
foot cleansing2 products
lip balm with SPF2 products
eyelash glue2 products
cuticle treatment1 products
tooth whitening1 products
hair relaxer1 products
lip plumper1 products
baby oil1 products
pore strips1 products
tanning oil1 products


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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
356 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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