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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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foundation556 products
shampoo338 products
facial moisturizer/treatment301 products
moisturizer289 products
conditioner277 products
body wash/cleanser231 products
concealer221 products
facial cleanser207 products
serums & essences173 products
mask164 products
liquid hand soap156 products
mascara152 products
eye shadow139 products
daily use with SPF135 products
exfoliant/scrub102 products
around-eye cream93 products
blush90 products
toners/astringents87 products
body firming lotion87 products
hair treatment/serum85 products
bronzer/highlighter82 products
hair styling aide79 products
makeup primer65 products
lipstick59 products
makeup remover57 products
hand cream55 products
recreational sunscreen53 products
eye liner47 products
styling gel/lotion41 products
toothpaste41 products
facial powder39 products
bubble bath38 products
lip gloss38 products
hair color and bleaching37 products
anti-aging36 products
setting powder/spray35 products
antiperspirant/deodorant31 products
baby wipes30 products
mouthwash29 products
29 products
baby shampoo27 products
detangler25 products
sunless tanning23 products
brow liner23 products
baby soap22 products
shaving cream21 products
CC cream18 products
hair spray16 products
baby lotion16 products
BB cream16 products
body spray15 products
lip balm15 products
baby toothpaste14 products
beard care14 products
after sun product13 products
hand sanitizer12 products
after shave12 products
bath oil/salts/soak10 products
baby bubble bath10 products
eye makeup remover10 products
foot moisturizer9 products
bar soap9 products
glitter9 products
shaving cream (men's)8 products
baby sunscreen7 products
styling mousse/foam6 products
lip liner6 products
antiperspirant/deodorant (men's)6 products
oil controller5 products
damaged skin treatment4 products
body oil3 products
other eye makeup3 products
beard cleanser3 products
muscle/joint soreness2 products
diaper cream2 products
hair-loss treatment2 products
nail polish2 products
depilatory2 products
hair relaxer2 products
polish remover2 products
lip balm with SPF2 products
cuticle treatment1 products
nail treatment1 products
fragrance for women1 products
lip plumper1 products
foot cleansing1 products
baby oil1 products
foot odor control1 products
tanning oil1 products


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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
356 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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