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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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foundation489 products
moisturizer225 products
shampoo208 products
concealer189 products
facial moisturizer/treatment174 products
body wash/cleanser154 products
conditioner139 products
facial cleanser127 products
serums & essences102 products
mask100 products
liquid hand soap86 products
moisturizer with SPF80 products
mascara75 products
blush60 products
exfoliant/scrub57 products
bronzer/highlighter57 products
eye shadow56 products
around-eye cream51 products
beach & sport sunscreen44 products
toners/astringents44 products
makeup remover38 products
facial powder37 products
makeup primer36 products
hair color and bleaching35 products
hair treatment/serum33 products
hand cream29 products
baby shampoo28 products
body firming lotion25 products
styling gel/lotion24 products
eye liner23 products
baby soap23 products
hair styling aide20 products
bubble bath19 products
baby wipes19 products
lip gloss19 products
toothpaste18 products
shaving cream18 products
anti-aging17 products
brow liner17 products
lipstick17 products
CC cream16 products
sunless tanning15 products
baby lotion15 products
baby bubble bath13 products
antiperspirant/deodorant13 products
detangler12 products
lip balm12 products
hair spray10 products
mouthwash10 products
hand sanitizer9 products
after shave8 products
foot moisturizer7 products
BB cream7 products
shaving cream (men's)7 products
bath oil/salts/soak6 products
bar soap6 products
lip liner6 products
after sun product6 products
body spray5 products
nail treatment5 products
baby toothpaste5 products
eye makeup remover5 products
glitter5 products
oil controller4 products
styling mousse/foam4 products
beard care4 products
diaper cream2 products
antiperspirant/deodorant (men's)2 products
2 products
lip balm with SPF2 products
nail polish2 products
other eye makeup2 products
body oil1 products
hair relaxer1 products
polish remover1 products
muscle/joint soreness1 products
hair-loss treatment1 products
cuticle treatment1 products
lip plumper1 products
baby oil1 products
baby sunscreen1 products
damaged skin treatment1 products
tanning oil1 products


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Concern Reference
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
356 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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