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POLYSORBATE-80

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low) and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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facial moisturizer/treatment75 products
mask68 products
moisturizer58 products
mouthwash41 products
bath oil/salts/soak38 products
daily use with SPF36 products
serums & essences35 products
toothpaste34 products
facial cleanser29 products
hair color and bleaching27 products
around-eye cream25 products
hair styling aide22 products
body wash/cleanser20 products
makeup primer20 products
hair treatment/serum19 products
hand cream18 products
conditioner17 products
mascara16 products
bronzer/highlighter16 products
exfoliant/scrub16 products
shampoo15 products
toners/astringents15 products
eye liner14 products
concealer12 products
BB cream12 products
body firming lotion11 products
styling gel/lotion11 products
hair spray11 products
11 products
recreational sunscreen11 products
blush10 products
foundation10 products
after sun product9 products
brow liner9 products
anti-aging8 products
sunless tanning7 products
lipstick7 products
nail treatment6 products
lip balm with SPF6 products
hair-loss treatment5 products
makeup remover5 products
liquid hand soap5 products
eye shadow4 products
body spray4 products
detangler4 products
bar soap3 products
beard care3 products
facial powder3 products
baby shampoo2 products
foot moisturizer2 products
styling mousse/foam2 products
tooth whitening2 products
after shave2 products
lip balm2 products
damaged skin treatment2 products
foot cleansing2 products
baby soap2 products
foot odor control2 products
baby oil1 products
lip plumper1 products
baby sunscreen1 products
other eye makeup1 products
baby bubble bath1 products
antiperspirant/deodorant (men's)1 products
bubble bath1 products
fragrance for women1 products
oil controller1 products
setting powder/spray1 products

Contamination concerns

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Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityScorecard.org Toxicity Information
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
122419 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data Sources

  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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