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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low) and Contamination concerns (high)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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conditioner140 products
moisturizer131 products
daily use with SPF112 products
facial moisturizer/treatment90 products
eye shadow71 products
body firming lotion69 products
mask54 products
hair styling aide51 products
hair treatment/serum50 products
recreational sunscreen48 products
serums & essences45 products
exfoliant/scrub41 products
foundation40 products
hand cream32 products
sunless tanning30 products
facial cleanser29 products
makeup primer17 products
mascara17 products
around-eye cream16 products
lipstick13 products
styling gel/lotion13 products
12 products
foot moisturizer12 products
hair color and bleaching12 products
anti-aging11 products
baby lotion11 products
bronzer/highlighter11 products
BB cream10 products
glitter9 products
hair-loss treatment9 products
beard care9 products
antiperspirant/deodorant8 products
baby sunscreen6 products
eye liner6 products
shaving cream6 products
body wash/cleanser6 products
blush5 products
lip balm5 products
after shave4 products
detangler4 products
bath oil/salts/soak4 products
foot cleansing4 products
makeup remover4 products
tanning oil4 products
after sun product4 products
brow liner4 products
hair relaxer3 products
muscle/joint soreness3 products
concealer3 products
shampoo2 products
styling mousse/foam2 products
hair spray2 products
shaving cream (men's)2 products
eyelash glue2 products
foot odor control1 products
eye makeup remover1 products
pore strips1 products
other eye makeup1 products
damaged skin treatment1 products
cuticle treatment1 products
beard cleanser1 products
diaper cream1 products
toners/astringents1 products

Contamination concerns

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Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
222 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.


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