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POLYSORBATE-20

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low) and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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serums & essences198 products
facial moisturizer/treatment187 products
mask154 products
shampoo151 products
body wash/cleanser146 products
foundation143 products
facial cleanser117 products
toners/astringents106 products
hair styling aide97 products
daily use with SPF93 products
bronzer/highlighter86 products
hair treatment/serum85 products
exfoliant/scrub83 products
liquid hand soap82 products
conditioner79 products
moisturizer76 products
styling gel/lotion67 products
makeup remover59 products
concealer50 products
around-eye cream47 products
recreational sunscreen46 products
hair spray36 products
after sun product36 products
CC cream35 products
mouthwash32 products
makeup primer31 products
blush30 products
setting powder/spray29 products
styling mousse/foam28 products
body spray28 products
body firming lotion28 products
detangler27 products
baby wipes25 products
facial powder24 products
hand sanitizer23 products
bath oil/salts/soak21 products
sunless tanning19 products
anti-aging18 products
lipstick18 products
antiperspirant/deodorant16 products
eye liner16 products
hand cream16 products
BB cream15 products
bubble bath14 products
baby lotion14 products
after shave13 products
foot cleansing12 products
shaving cream12 products
mascara10 products
brow liner9 products
eye shadow8 products
baby shampoo8 products
8 products
foot moisturizer7 products
beard care6 products
eye makeup remover5 products
baby soap5 products
foot odor control5 products
body oil4 products
baby bubble bath4 products
baby sunscreen4 products
nail treatment3 products
shaving cream (men's)3 products
hair relaxer3 products
other eye makeup3 products
hair color and bleaching2 products
tooth whitening2 products
polish remover2 products
antiperspirant/deodorant (men's)2 products
bar soap2 products
damaged skin treatment2 products
nail polish2 products
beard cleanser2 products
hair-loss treatment1 products
tanning oil1 products
skin fading/lightener1 products
muscle/joint soreness1 products
cuticle treatment1 products
fragrance for women1 products
depilatory1 products
lip balm1 products
lip gloss1 products
diaper cream1 products
glitter1 products
baby oil1 products

Contamination concerns

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Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
2265 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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