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POLYSORBATE-20

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (low) and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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foundation101 products
serums & essences68 products
moisturizer with SPF60 products
facial moisturizer/treatment56 products
bronzer/highlighter27 products
blush27 products
body wash/cleanser25 products
toners/astringents24 products
facial cleanser23 products
concealer22 products
beach & sport sunscreen21 products
facial powder19 products
liquid hand soap17 products
shampoo14 products
mask13 products
makeup remover10 products
around-eye cream10 products
BB cream9 products
moisturizer8 products
styling gel/lotion7 products
hair styling aide7 products
mouthwash6 products
makeup primer6 products
hair spray6 products
CC cream5 products
exfoliant/scrub4 products
eye liner4 products
brow liner4 products
baby wipes4 products
conditioner3 products
other eye makeup3 products
detangler3 products
baby lotion3 products
hair treatment/serum3 products
oil controller2 products
mascara2 products
hand cream2 products
lipstick2 products
after sun product2 products
antiperspirant/deodorant (men's)2 products
after shave1 products
baby soap1 products
styling mousse/foam1 products
shaving cream1 products
body firming lotion1 products
foot moisturizer1 products
baby sunscreen1 products
beard oil1 products
baby shampoo1 products
eye makeup remover1 products
sunless tanning1 products
shaving cream (men's)1 products
body spray1 products
antiperspirant/deodorant1 products
hand sanitizer1 products
eye shadow1 products
body oil1 products

Contamination concerns

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Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
2265 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Data Sources

  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

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