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Data: Limited

Polyaminopropyl Biguanide

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

Other Concerns

Use restrictions (high) and Irritation (skin, eyes, or lungs) (low)

SYNONYMS

● IMIDODICARBONIMIDIC DIAMIDE, N-(3-AMINOPROPYL)- HOMOPOLYMER
● N-(3-AMINOPROPYL)- HOMOPOLYMER IMIDODICARBONIMIDIC DIAMIDE
● POLYAMINOPROPYL BIGUANIDE
● POLYHEXANIDE

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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foundation41 products
recreational sunscreen23 products
19 products
baby wipes16 products
makeup remover13 products
facial cleanser11 products
eye shadow6 products
baby sunscreen6 products
daily use with SPF6 products
concealer5 products
setting powder/spray4 products
hand sanitizer4 products
blush4 products
makeup removing wipes3 products
eye makeup remover3 products
hair styling aide3 products
detangler2 products
body cleansing wipes2 products
shampoo2 products
mascara2 products
facial moisturizer/treatment2 products
body wash/cleanser2 products
facial cleansing wipes1 products
bronzer/highlighter1 products
baby toothpaste1 products
toners/astringents1 products
hair color and bleaching1 products
liquid hand soap1 products
antiperspirant/deodorant1 products
styling mousse/foam1 products
conditioner1 products
moisturizer1 products

Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Banned or found unsafe for use in cosmeticsOpen scientific literature
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Determined safe for use in cosmetics, subject to concentration or use limitations - anyOpen scientific literature

Allergies/immunotoxicity

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CONCERN REFERENCE
any or allergies - weight of evidence unknown/unassessedOpen scientific literature

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
any irritation - weight of evidence unknown/unassessedOpen scientific literature

Data gaps

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CONCERN REFERENCE
Insufficient data to determine safetyOpen scientific literature
29 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed
  • Open scientific/peer reviewed literature
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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September 23, 2023 | Los Angeles, CA

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