Other ConcernsUse restrictions (moderate), Endocrine disruption (low), Non-reproductive organ system toxicity (moderate), and Contamination concerns (high)
Unacceptable: EWG VERIFIED products cannot contain this ingredient
This ingredient is derived from the placenta, an organ that develops in female mammals during pregnancy, lining the uterine wall and attached by the umbilical cord to provide nourishment and oxygen to the fetus. The placenta produces progesterone, estrogen, and other hormones, which raise potential health concerns in personal care products. In one study four girls between one and eight years of age developed breasts or pubic hair two to 24 months after starting the use of estrogen- or placenta-containing hair products. Their breasts and public hair regressed when they stopped using the products. No other cause for early sexual development was found. <a href='http://www.ewg.org/reports/skindeep2/references.php'>(Tiwary 1998)</a>.
See how this product scores for common concerns.
LOWAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
Organ system toxicity (non-reproductive)
|Potential risk of infectious disease - Must be free of detectable pathogenic viruses or infectious agents||Cosmetic Ingredient Review Assessments|
|Potential risk of infectious disease - any||FDA Ingredients with Bovine Spongiform Encephalopathy Concern|
|One or more studies show weak endocrine disruption||Open scientific literature|
|endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study||Cosmetic Ingredient Review Assessments|
|Insufficient data to determine safety||Cosmetic Ingredient Review Assessments|
|223 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - endocrine||Cosmetic Ingredient Review Assessments|
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- FDA (U.S. Food and Drug Administration). 2000. FDA Center for Food Safety and Applied Nutrition. Cosmetics Compliance Program. Domestic Cosmetics Program. Coverage of Bovine-Derived Ingredients for Bovine Spongiform Encephalopathy (BSE). Issued July 31, 2000.
- Open scientific/peer reviewed literature
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.