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Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate), Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (high)


Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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foundation676 products
eye shadow620 products
lipstick462 products
moisturizer with SPF371 products
concealer356 products
facial moisturizer/treatment303 products
serums & essences283 products
bronzer/highlighter275 products
moisturizer257 products
beach & sport sunscreen236 products
eye liner219 products
mask205 products
blush171 products
facial cleanser136 products
conditioner127 products
mascara121 products
shampoo116 products
lip gloss110 products
body wash/cleanser103 products
brow liner92 products
facial powder89 products
makeup primer79 products
lip liner61 products
around-eye cream56 products
lip balm52 products
makeup remover52 products
hand cream51 products
exfoliant/scrub47 products
toners/astringents47 products
liquid hand soap37 products
styling gel/lotion36 products
hair styling aide35 products
BB cream34 products
hair treatment/serum30 products
shaving cream27 products
hair color and bleaching24 products
anti-aging22 products
baby sunscreen22 products
lip balm with SPF17 products
hair spray16 products
other eye makeup16 products
CC cream14 products
detangler14 products
body firming lotion14 products
lip plumper14 products
sunless tanning12 products
baby lotion12 products
after shave11 products
oil controller11 products
baby shampoo11 products
antiperspirant/deodorant10 products
baby soap9 products
shaving cream (men's)9 products
eye makeup remover8 products
bubble bath7 products
styling mousse/foam6 products
baby wipes5 products
glitter5 products
foot moisturizer5 products
body spray4 products
bath oil/salts/soak4 products
body oil4 products
eyelash glue4 products
after sun product3 products
nail treatment2 products
hair relaxer2 products
baby bubble bath2 products
foot odor control1 products
baby oil1 products
depilatory1 products
polish remover1 products
muscle/joint soreness1 products
skin fading/lightener1 products
body powder1 products
diaper cream1 products
fragrance for men1 products
bar soap1 products
antiperspirant/deodorant (men's)1 products
nail polish1 products
beard oil1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling

Occupational hazards

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Concern Reference
Allowed workplace exposures restricted to low dosesCPS&Q - Classification & Labelling

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in cosmetics (concentration limit)Japan's Standards for Cosmetics

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of nervous toxicityNational Library of Medicine, HazMap database
Classified as toxic or harmfulCPS&Q - Classification & Labelling
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List


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Concern Reference
Limited evidence of skin and immune system toxicity or allergiesHeidary N, Cohen DE Hypersensitivity reactions to vaccine components. Dermatitis. 2005 Sep;16(3):115-20.

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
279 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed


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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List


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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • National Library of Medicine, HazMap database
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Heidary N, Cohen DE Hypersensitivity reactions to vaccine components. Dermatitis. 2005 Sep;16(3):115-20.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data.


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