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Data: Limited

Panthenol

IMAGE SOURCE: PubChem

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Other Concerns

Multiple, additive exposure sources (low)

SYNONYMS

● 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL- BUTANAMIDE
● 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYLBUTANAMIDE
● BUTANAMIDE, 2,4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3,3-DIMETHYL-
● BUTANAMIDE, 2,4DIHYDROXYN(3HYDROXYPROPYL)3,3DIMETHYL,(+/)
● D-PANTOTHENYL ALCOHOL
● DEXPANTHENOL
● DL-PANTOTHENYL ALCOHOL
● PANTHENOL
● PANTHENOL , DL-FORM
● PANTOTHENOL
● PANTOTHENYL ALCOHOL
● PROVITAMIN B5

Restricted

Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation


Panthenol is a form of vitamin B5, used as a moisturizer and lubricating compound. This ingredient is listed in the PETA's Caring Consumer guide as a substance that can be of either animal or plant origin.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • LOW
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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conditioner943 products
shampoo929 products
facial moisturizer/treatment458 products
moisturizer398 products
mask372 products
hair treatment/serum357 products
hair styling aide276 products
mascara268 products
serums & essences248 products
body wash/cleanser237 products
facial cleanser226 products
foundation221 products
brow liner158 products
around-eye cream155 products
hair spray152 products
styling gel/lotion150 products
toners/astringents98 products
daily use with SPF94 products
recreational sunscreen93 products
exfoliant/scrub72 products
concealer71 products
sunless tanning66 products
styling mousse/foam55 products
detangler55 products
liquid hand soap55 products
anti-aging48 products
antiperspirant/deodorant47 products
nail polish46 products
makeup remover45 products
makeup primer43 products
setting powder/spray43 products
hair color and bleaching42 products
hand cream41 products
bubble bath40 products
polish remover37 products
CC cream36 products
shaving cream33 products
eye shadow30 products
baby lotion28 products
bar soap28 products
after shave27 products
baby shampoo21 products
baby soap20 products
bronzer/highlighter19 products
lip balm18 products
17 products
beard care15 products
facial powder14 products
body spray14 products
damaged skin treatment12 products
eye liner12 products
body firming lotion12 products
beard cleanser12 products
hair-loss treatment11 products
shaving cream (men's)11 products
hand sanitizer10 products
baby sunscreen10 products
diaper cream9 products
nail treatment9 products
after sun product9 products
BB cream8 products
foot moisturizer7 products
tanning oil7 products
other eye makeup6 products
body oil6 products
foot cleansing5 products
lip balm with SPF5 products
skin fading/lightener4 products
bath oil/salts/soak4 products
fragrance for men4 products
cuticle treatment3 products
foot odor control2 products
baby bubble bath2 products
blush2 products
nail glue2 products
baby oil2 products
lip plumper2 products
makeup removing wipes2 products
facial cleansing wipes2 products
oil controller1 products
antiperspirant/deodorant (men's)1 products
eye makeup remover1 products
baby wipes1 products
muscle/joint soreness1 products
depilatory1 products
pore strips1 products
eyelash glue1 products
vapor rubs1 products

Multiple, additive exposure sources

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CONCERN REFERENCE
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Data gaps

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CONCERN REFERENCE
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
326 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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September 23, 2023 | Los Angeles, CA

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