- †Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.
Other ConcernsEnhanced skin absorption, Use restrictions (moderate), Endocrine disruption (low), Contamination concerns (high), and Biochemical or cellular level changes (high)
SYNONYMS2-ETHYLHEXYL 4-(DIMETHYLAMINO)BENZOATE, 2-ETHYLHEXYL 4-DIMETHYL-AMINOBENZOATE, 2-ETHYLHEXYL ESTER 4-(DIMETHYLAMINO)BENZOIC ACID, 2-ETHYLHEXYL ESTER BENZOIC ACID, 4-(DIMETHYLAMINO)-, 2-ETHYLHEXYL P-DIMETHYLAMINOBENZOATE, 2-ETHYLHEXYL PARADIMETHYLAMINO BENZOATE, 4-(DIMETHYLAMINO)- 2-ETHYLHEXYL ESTER BENZOIC ACID, 4-(DIMETHYLAMINO)- OCTYL ESTER BENZOIC ACID, 4-(DIMETHYLAMINO)BENZOIC ACID, 2-ETHYLHEXYL ESTER, ARLATONE UVB, BENZOIC ACID, 4(DIMETHYLAMINO), 2ETHYLHEXYL ESTER, BENZOIC ACID, 4-(DIMETHYLAMINO)-, 2-ETHYLHEXYL ESTER, BENZOIC ACID, 4-(DIMETHYLAMINO)-, OCTYL ESTER, BENZOIC ACID, P-(DIMETHYLAMINO)-, 2-ETHYLHEXYL ESTER, CARALOE SNOW & SUN LIP BALM, EINECS 244-289-3, ESCALOL 507, ETHYLHEXYL DIMETHYL PABA, EUSOLEX 6007, HSDB 7169, OCTY L DIMETHYL PABA, OCTYL DIMETHYL P-AMINOBENZOATE, OCTYL DIMETHYL PABA, OCTYL ESTER BENZOIC ACID, 4-(DIMETHYLAMINO)-, PADIMATE O, PADIMATE O (OCTYL DIMETHYL PABA | PABA ESTER), PADIMATE-O, PHOTOPLEX, PO, PRESUN 15, PRESUN 46, and RADIACARE LIP BALM
A derivative of the once-popular PABA sunscreen ingredient, research shows this chemical releases free radicals, damages DNA, has estrogenic activity, and causes allergic reactions in some people.
See how this product scores for common concerns.
LOWAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
Enhanced skin absorption
|Penetration enhancer||Open scientific literature|
Biochemical or cellular level changes
|Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease.||Open scientific literature|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)||Japan's Standards for Cosmetics|
|One or more in vitro tests on mammalian cells show positive mutation results||Open scientific literature|
|One or more studies show weak endocrine disruption||Open scientific literature|
|Associated with immunotoxicity or allergies||Open scientific literature|
|Suspected to be an environmental toxin||Environment Canada Domestic Substance List|
Organ system toxicity (non-reproductive)
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
Persistence and bioaccumulation
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
|20352 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
- Open scientific/peer reviewed literature
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.