Other Concerns
Use restrictions (high), Multiple, additive exposure sources (low), and Biochemical or cellular level changes (high)SYNONYMS
Unacceptable
Unacceptable: EWG VERIFIED products cannot contain this ingredient
A once-common sunscreen ingredient, now avoided due to allergic dermatitis and photosensitivity. Research indicates PABA has carcinogenic potential. PABA derivatives are now more commonly used, but these too may have health concerns.
Common concerns
See how this product scores for common concerns.
-
LOWCancer
-
MODERATEAllergies & Immunotoxicity
-
LOWDevelopmental and Reproductive Toxicity
-
HIGHUse Restrictions
Ingredient concerns
- CONCERNS
- DATA SOURCES
Products with this Ingredient
Biochemical or cellular level changes
CONCERN | REFERENCE |
---|---|
Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | Open scientific literature |
Use restrictions
CONCERN | REFERENCE |
---|---|
Violation of government restrictions - Banned or found unsafe for use in cosmetics | Canada - Prohibited and Restricted Cosmetics Ingredients |
Violation of government restrictions - Banned or found unsafe for use in cosmetics | CosIng |
Enhanced skin absorption
CONCERN | REFERENCE |
---|---|
Absorbs into the skin | Open scientific literature |
Allergies/immunotoxicity
CONCERN | REFERENCE |
---|---|
Human any toxicant or allergen - moderate evidence | Open scientific literature |
Limited evidence of immune system toxicity or allergies | Open scientific literature |
Multiple, additive exposure sources
CONCERN | REFERENCE |
---|---|
Used in food or as an additive with limited or no toxicity information available | FDA Everything Added to Food |
Designated as safe for general or specific, limited use in food | FDA Food Additive Status |
Data gaps
CONCERN | REFERENCE |
---|---|
5422 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Cancer
CONCERN | REFERENCE |
---|---|
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps | Int'l Agency for Research on Cancer (IARC) - Carcinogens |
Ecotoxicology
CONCERN | REFERENCE |
---|---|
Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
CONCERN | REFERENCE |
---|---|
Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
CONCERN | REFERENCE |
---|---|
Not suspected to be persistent | Environment Canada Domestic Substance List |
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
- Open scientific/peer reviewed literature
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
Understanding scores
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.
HOW WE DETERMINE SCORESHazard score
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
Data availability
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.