Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
Organ system toxicity (non-reproductive)
|Known human respiratory toxicant||EPA Hazardous Air Pollutants|
|Classified as toxic or harmful||CPS&Q - Classification & Labelling|
|Limited evidence of gastrointestinal or liver toxicity||National Library of Medicine HazMap|
|One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Toxic Release Inventory PBTs|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
Irritation (skin, eyes, or lungs)
|Classified as irritant||CPS&Q - Classification & Labelling|
|Limited evidence of eye irritation||Open scientific literature|
|Limited evidence of eye irritation||Open scientific literature|
|Allowed workplace exposures restricted to low doses||CPS&Q - Classification & Labelling|
|Human skin toxicant or allergen - strong evidence||Cosmetic Ingredient Review Assessments|
|Limited evidence of immune system toxicity or allergies||CPS&Q - Classification & Labelling|
|Limited evidence of immune system toxicity or allergies||National Library of Medicine HazMap|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any||Open scientific literature|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any||CosIng|
|Determined safe for use in cosmetics, subject to concentration or use limitations - any||CTFA International Cosmetic Ingredient Dictionary and Handbook|
|Cancer - limited evidence||CTFA International Cosmetic Ingredient Dictionary and Handbook|
|Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps||Int'l Agency for Research on Cancer (IARC) - Carcinogens|
|Wildlife and environmental toxicity||CPS&Q - Classification & Labelling|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product||Cosmetic Ingredient Review Assessments|
|Insufficient data to determine safety||Cosmetic Ingredient Review Assessments|
|1988 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any||Cosmetic Ingredient Review Assessments|
Persistence and bioaccumulation
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
|Not suspected to be persistent||Environment Canada Domestic Substance List|
- EPA (U.S. Environmental Protection Agency). 2005. Office of Air. The 112(b)1 Hazardous Air Pollutants List (as modified). Last modified: 12 Dec 2005.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- Open scientific/peer reviewed literature
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
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EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
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