Octisalate
- Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.
Other Concerns
Enhanced skin absorption, Use restrictions (moderate), Endocrine disruption (low), and Biochemical or cellular level changes (high)SYNONYMS
Restricted
Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation
Octisalate is a sunscreen ingredient with a generally good safety profile. It can stabilize avobenzone and result in longer-lasting sun protection.
Common concerns
See how this product scores for common concerns.
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LOWCancer
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LOWAllergies & Immunotoxicity
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LOWDevelopmental and Reproductive Toxicity
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MODERATEUse Restrictions
Ingredient concerns
- CONCERNS
- DATA SOURCES
Products with this Ingredient
recreational sunscreen | 484 products |
daily use with SPF | 280 products |
foundation | 131 products |
fragrance for women | 124 products |
CC cream | 71 products |
fragrance for men | 54 products |
baby sunscreen | 49 products |
lip balm with SPF | 47 products |
body spray | 31 products |
conditioner | 26 products |
facial moisturizer/treatment | 22 products |
shampoo | 19 products |
hair treatment/serum | 16 products |
blush | 12 products |
11 products | |
body oil | 11 products |
tanning oil | 9 products |
hair styling aide | 8 products |
body wash/cleanser | 7 products |
makeup primer | 7 products |
lip balm | 7 products |
bronzer/highlighter | 6 products |
BB cream | 5 products |
facial cleanser | 5 products |
hair spray | 5 products |
hand sanitizer | 4 products |
styling mousse/foam | 4 products |
skin fading/lightener | 4 products |
styling gel/lotion | 3 products |
serums & essences | 3 products |
setting powder/spray | 3 products |
moisturizer | 3 products |
after shave | 3 products |
lipstick | 2 products |
exfoliant/scrub | 2 products |
detangler | 2 products |
concealer | 1 products |
hair color and bleaching | 1 products |
toners/astringents | 1 products |
after sun product | 1 products |
around-eye cream | 1 products |
lip gloss | 1 products |
hand cream | 1 products |
sunless tanning | 1 products |
Enhanced skin absorption
CONCERN | REFERENCE |
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Penetration enhancer | Open scientific literature |
Absorbs into the skin | Open scientific literature |
Biochemical or cellular level changes
CONCERN | REFERENCE |
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Produces excess reactive oxygen species that can interfere with cellular signaling, cause mutations, lead to cell death and may be implicated in cardiovascular disease. | Open scientific literature |
Does not produces excess reactive oxygen species or other harmful biochemical changes. | Open scientific literature |
Use restrictions
CONCERN | REFERENCE |
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Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | Japan's Standards for Cosmetics |
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | Cosmetic Ingredient Review Assessments |
Allergies/immunotoxicity
CONCERN | REFERENCE |
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One or more human case studies show possible immune or allergenic effects | Open scientific literature |
Endocrine disruption
CONCERN | REFERENCE |
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Associated with endocrine disruption | Open scientific literature |
Ecotoxicology
CONCERN | REFERENCE |
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Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Organ system toxicity (non-reproductive)
CONCERN | REFERENCE |
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Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
CONCERN | REFERENCE |
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Not suspected to be persistent | Environment Canada Domestic Substance List |
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data gaps
CONCERN | REFERENCE |
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2123 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
- Open scientific/peer reviewed literature
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Understanding scores
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.
HOW WE DETERMINE SCORESHazard score
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
Data availability
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.