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NIACINAMIDE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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facial moisturizer/treatment357 products
serums & essences254 products
mask167 products
foundation145 products
daily use with SPF122 products
shampoo113 products
conditioner108 products
concealer102 products
CC cream93 products
moisturizer91 products
facial cleanser86 products
around-eye cream77 products
toners/astringents69 products
makeup primer46 products
body wash/cleanser43 products
nail polish39 products
setting powder/spray38 products
anti-aging36 products
exfoliant/scrub26 products
hair treatment/serum24 products
body firming lotion22 products
recreational sunscreen17 products
hand cream12 products
makeup remover12 products
bronzer/highlighter10 products
hair-loss treatment9 products
8 products
facial powder8 products
BB cream8 products
hair styling aide6 products
bar soap6 products
mascara6 products
hair color and bleaching6 products
skin fading/lightener6 products
lipstick6 products
blush6 products
after shave5 products
baby lotion5 products
after sun product5 products
hair spray5 products
damaged skin treatment4 products
styling gel/lotion4 products
foot moisturizer4 products
beard oil4 products
beard care4 products
liquid hand soap3 products
body oil3 products
lip balm3 products
antiperspirant/deodorant3 products
detangler3 products
hand sanitizer3 products
lip gloss3 products
bath oil/salts/soak2 products
body spray2 products
nail treatment2 products
baby soap2 products
eye shadow2 products
eye liner1 products
oil controller1 products
shaving cream1 products
pore strips1 products
depilatory1 products
shaving cream (men's)1 products
baby sunscreen1 products
foot cleansing1 products
muscle/joint soreness1 products
baby bubble bath1 products
baby shampoo1 products
beard cleanser1 products

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
53042 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

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