Other ConcernsUse restrictions (high), Ecotoxicology (low), and Irritation (skin, eyes, or lungs) (moderate)
SYNONYMS3(2H)ISOTHIAZOLONE, 5CHLORO2METHYL, 4-ISOTHIAZOLIN-3-ONE, 5-CHLORO-2-METHYL-, 5-CHLORO-2-METHYL- 4-ISOTHIAZOLIN-3-ONE, 5-CHLORO-2-METHYL-2H-ISOTHIAZOL-3-ONE, 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE, METHYLCHLOROISOTHIAZOLINONE, and METHYLCHLOROTHIAZOLINONE
Methylchloroisothiazolinone is a widely-used preservative; has been associated with allergic reactions.
See how this product scores for common concerns.
MODERATEAllergies & Immunotoxicity
LOWDevelopmental and Reingredientive Toxicity
- DATA SOURCES
Products with this Ingredient
|body wash/cleanser||481 products|
|liquid hand soap||408 products|
|bubble bath||84 products|
|hair color and bleaching||84 products|
|facial cleanser||54 products|
|hair treatment/serum||53 products|
|bath oil/salts/soak||20 products|
|hair styling aide||17 products|
|styling gel/lotion||13 products|
|baby shampoo||11 products|
|baby bubble bath||10 products|
|baby wipes||8 products|
|baby soap||7 products|
|beard cleanser||6 products|
|hand sanitizer||5 products|
|bar soap||4 products|
|after sun product||3 products|
|shaving cream||2 products|
|makeup remover||2 products|
|hair relaxer||2 products|
|baby oil||2 products|
|baby lotion||2 products|
|body firming lotion||2 products|
|styling mousse/foam||2 products|
|beard care||2 products|
|foot moisturizer||1 products|
|eye liner||1 products|
|foot cleansing||1 products|
|damaged skin treatment||1 products|
|sunless tanning||1 products|
|hair spray||1 products|
|Violation of government restrictions - Banned or found unsafe for use in cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
|Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - any||Open scientific literature|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmetics when combined with certain other ingredients||Japan's Standards for Cosmetics|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
|Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications||Cosmetic Ingredient Review Assessments|
Irritation (skin, eyes, or lungs)
|Possible human skin irritant||Open scientific literature|
|Human skin toxicant or allergen - strong evidence||Cosmetic Ingredient Review Assessments|
|Human skin toxicant or allergen - moderate evidence||Open scientific literature|
|One or more human case studies show significant skin or allergenic effects||Open scientific literature|
|Limited evidence of immune system toxicity or allergies||Scorecard.org Toxicity Information|
|Limited evidence of immune system toxicity or allergies||National Library of Medicine HazMap|
|Mutagen - limited evidence||Open scientific literature|
|Wildlife and environmental toxicity||Open scientific literature|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product||Cosmetic Ingredient Review Assessments|
|232 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
Organ system toxicity (non-reproductive)
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
Persistence and bioaccumulation
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- Open scientific/peer reviewed literature
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.