Other ConcernsUse restrictions (high), Endocrine disruption (moderate), Persistence and bioaccumulation (moderate), Ecotoxicology (low), and Occupational hazards (high)
Unacceptable: EWG VERIFIED products cannot contain this ingredient
Ketoconazole is a heterocyclic compound.
See how this product scores for common concerns.
LOWAllergies & Immunotoxicity
MODERATEDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|styling gel/lotion||1 products|
|Violation of government restrictions - Banned or found unsafe for use in cosmetics||CosIng|
|Allowed workplace exposures restricted to low doses||Open scientific literature|
|Human endocrine disruptor - strong evidence||European Commission on Endocrine Disruption|
|Limited evidence of endocrine disruption||Scorecard.org Toxicity Information|
|endocrine - weight of evidence unknown/unassessed/unreview: published lit review or major tox study||Our Stolen Future Endocrine Disruptors|
Persistence and bioaccumulation
|Persistent or bioaccumulative and moderate to high toxicity concern in humans||Open scientific literature|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
|Limited evidence of reproductive toxicity||CPS&Q - Classification & Labelling|
|Wildlife and environmental toxicity||CPS&Q - Classification & Labelling|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|28566 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
Organ system toxicity (non-reproductive)
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- Open scientific/peer reviewed literature
- EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- Colborn T, D Dumanoski, JP Myers. 2006. Widespread Pollutants with Endocrine-disrupting Effects. Updated from original listing in "Our Stolen Future" (1996).
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.