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ISOPROPYL ALCOHOL

Score:

Data: Good

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption, Non-reproductive organ system toxicity (moderate), Irritation (skin, eyes, or lungs) (high), and Occupational hazards (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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nail polish482 products
conditioner243 products
hair color and bleaching130 products
hair treatment/serum52 products
hand sanitizer50 products
shampoo48 products
foundation42 products
lip gloss29 products
hair styling aide27 products
mascara14 products
nail treatment13 products
mask13 products
moisturizer8 products
detangler8 products
styling gel/lotion7 products
hair spray7 products
body wash/cleanser5 products
5 products
facial cleanser5 products
facial moisturizer/treatment4 products
toners/astringents4 products
after sun product4 products
serums & essences3 products
after shave3 products
daily use with SPF2 products
foot odor control2 products
styling mousse/foam2 products
foot moisturizer2 products
exfoliant/scrub2 products
body firming lotion2 products
hand cream2 products
makeup remover2 products
makeup primer2 products
damaged skin treatment1 products
nail glue1 products
hair-loss treatment1 products
BB cream1 products
body spray1 products
lip balm1 products
hair relaxer1 products
beard cleanser1 products
lipstick1 products
brow liner1 products
beard care1 products
CC cream1 products
body oil1 products
anti-aging1 products
bronzer/highlighter1 products
eye liner1 products
antiperspirant/deodorant1 products

Enhanced skin absorption

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Concern Reference
Penetration enhancerOpen scientific literature

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as any irritantOpen scientific literature

Occupational hazards

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Concern Reference
Moderate evidence of occupational hazardsOpen scientific literature
Limited evidence of occupational hazardsOpen scientific literature

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as toxic or harmful.Open scientific literature
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Associated with any toxicityOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Limited evidence of any toxicity or allergiesOpen scientific literature

Data gaps

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Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
112675 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyCosmetic Ingredient Review Assessments

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Cancer

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Concern Reference
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsInt'l Agency for Research on Cancer (IARC) - Carcinogens

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Neurotoxicity

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Concern Reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Open scientific/peer reviewed literature
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.

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