- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
- Products with this ingredient are allowed for use in EWG VERIFIED but must meet use restrictions and warnings based on EWG review of company data.
- This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
- Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.
Other ConcernsUse restrictions (moderate), Non-reproductive organ system toxicity (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (moderate), and Contamination concerns (high)
Restricted: EWG VERIFIED products cannot contain this ingredient without adequate substantiation
isobutane is a hydrocarbon gas; used as a propellant in aerosolized products.
See how this product scores for common concerns.
MODERATEAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|styling mousse/foam||71 products|
|recreational sunscreen||66 products|
|shaving cream||60 products|
|body spray||46 products|
|hair spray||45 products|
|antiperspirant/deodorant (men's)||39 products|
|shaving cream (men's)||37 products|
|hair color and bleaching||29 products|
|hair styling aide||20 products|
|hair treatment/serum||18 products|
|hair-loss treatment||15 products|
|eye shadow||13 products|
|baby sunscreen||10 products|
|sunless tanning||5 products|
|facial moisturizer/treatment||4 products|
|BB cream||4 products|
|body wash/cleanser||4 products|
|tanning oil||3 products|
|styling gel/lotion||3 products|
|beard care||2 products|
|setting powder/spray||2 products|
|fragrance for men||2 products|
|nail glue||1 products|
|facial cleanser||1 products|
|hand sanitizer||1 products|
|body powder||1 products|
|bubble bath||1 products|
|foot odor control||1 products|
Organ system toxicity (non-reproductive)
|Classified as a high human health priority||Environment Canada Domestic Substance List|
|Classified as expected to be toxic or harmful||Environment Canada Domestic Substance List|
|Human any toxicant or allergen - strong evidence||Cosmetic Ingredient Review Assessments|
Irritation (skin, eyes, or lungs)
|Human any irritant - strong evidence||Cosmetic Ingredient Review Assessments|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Use is restricted in Canadian cosmetics||Canada - Prohibited and Restricted Cosmetics Ingredients|
Multiple, additive exposure sources
|Used in food or as an additive with limited or no toxicity information available||FDA Everything Added to Food|
|Designated as safe for general or specific, limited use in food||Cosmetic Ingredient Review Assessments|
|Designated as safe for general or specific, limited use in food||FDA Food Additive Status|
|Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product||Cosmetic Ingredient Review Assessments|
|470 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Occupational hazards related to handling||CPS&Q - Classification & Labelling|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
Persistence and bioaccumulation
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - any||Cosmetic Ingredient Review Assessments|
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Health Canada. 2007. List of Prohibited and Restricted Cosmetic Ingredients. Canada's Cosmetic Ingredient Hotlist. March 2007.
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED® mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.