- This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
Other ConcernsUse restrictions (high), Persistence and bioaccumulation (moderate), and Non-reproductive organ system toxicity (low)
SYNONYMS3-IODO-2-PROPYNYL BUTYLCARBAMATE, BUTYL-3-IODO-2-PROPYNYL ESTER CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYLCARBAMATE, BUTYLCARBAMIC ACID, 3-IODO-2-PROPYNYL ESTER, CARBAMIC ACID, BUTYL, 3IODO2PROPYNYL ESTER, CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYL ESTER, IDOPROPYNL BUTYLCARBAMATE, IODOPROPYL BUTYLCARBAMATE, IODOPROPYNL BUTYLCARBAMATE, IODOPROPYNYL BUTYLCARBAMATE, and IPBC
Unacceptable: EWG VERIFIED products cannot contain this ingredient
Iodopropynyl butylcarbamate is used as a preservative in cosmetic formulations; it is acutely toxic by inhalation and should not be used in products that can be aerosolized or inhaled.
See how this product scores for common concerns.
MODERATEAllergies & Immunotoxicity
LOWDevelopmental and Reproductive Toxicity
- DATA SOURCES
Products with this Ingredient
|body wash/cleanser||102 products|
|hair treatment/serum||57 products|
|liquid hand soap||47 products|
|hair styling aide||40 products|
|facial moisturizer/treatment||31 products|
|styling gel/lotion||30 products|
|eye liner||27 products|
|facial cleanser||26 products|
|daily use with SPF||22 products|
|eye shadow||20 products|
|makeup remover||19 products|
|serums & essences||17 products|
|hair color and bleaching||13 products|
|makeup primer||11 products|
|foot moisturizer||9 products|
|baby wipes||7 products|
|recreational sunscreen||7 products|
|styling mousse/foam||6 products|
|around-eye cream||6 products|
|hand cream||5 products|
|after sun product||5 products|
|eye makeup remover||5 products|
|CC cream||4 products|
|hair spray||4 products|
|hand sanitizer||3 products|
|foot cleansing||2 products|
|body firming lotion||2 products|
|setting powder/spray||2 products|
|brow liner||2 products|
|shaving cream||2 products|
|hair removal waxes||1 products|
|bubble bath||1 products|
|tanning oil||1 products|
|sunless tanning||1 products|
|body spray||1 products|
|skin fading/lightener||1 products|
|after shave||1 products|
|Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)||Cosmetic Ingredient Review Assessments|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)||Japan's Standards for Cosmetics|
|Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications||Cosmetic Ingredient Review Assessments|
|Human any toxicant or allergen - strong evidence||Cosmetic Ingredient Review Assessments|
|One or more human case studies show significant immune or allergenic effects||Open scientific literature|
Persistence and bioaccumulation
|Persistent or bioaccumulative and moderate to high toxicity concern in humans||Open scientific literature|
|Not suspected to be persistent||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
Organ system toxicity (non-reproductive)
|Limited evidence of gastrointestinal or liver toxicity||Scorecard.org Toxicity Information|
|One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Toxic Release Inventory PBTs|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
|Suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|Safety assessment was based on related chemical||Cosmetic Ingredient Review Assessments|
|50 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)||Cosmetic Ingredient Review Assessments|
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- Open scientific/peer reviewed literature
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.HOW WE DETERMINE SCORES
The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.
The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.