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Data: Fair

Iodopropynyl Butylcarbamate

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.

Other Concerns

Use restrictions (high) and Non-reproductive organ system toxicity (low)

SYNONYMS

3-IODO-2-PROPYNYL BUTYLCARBAMATE, BUTYL-3-IODO-2-PROPYNYL ESTER CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYLCARBAMATE, BUTYLCARBAMIC ACID, 3-IODO-2-PROPYNYL ESTER, CARBAMIC ACID, BUTYL, 3IODO2PROPYNYL ESTER, CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYL ESTER, IDOPROPYNL BUTYLCARBAMATE, IODOPROPYL BUTYLCARBAMATE, IODOPROPYNL BUTYLCARBAMATE, IODOPROPYNYL BUTYLCARBAMATE, and IPBC

Iodopropynyl butylcarbamate is used as a preservative in cosmetic formulations; it is acutely toxic by inhalation and should not be used in products that can be aerosolized or inhaled.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • MODERATE
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reproductive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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body wash/cleanser120 products
shampoo63 products
foundation63 products
hair treatment/serum59 products
conditioner58 products
mask53 products
hair styling aide42 products
exfoliant/scrub41 products
liquid hand soap40 products
styling gel/lotion40 products
moisturizer34 products
concealer29 products
facial cleanser28 products
facial moisturizer/treatment26 products
makeup remover23 products
daily use with SPF22 products
eye liner20 products
eye shadow19 products
serums & essences18 products
hair color and bleaching11 products
foot moisturizer10 products
makeup primer10 products
styling mousse/foam9 products
baby wipes9 products
anti-aging8 products
after sun product7 products
recreational sunscreen7 products
eye makeup remover6 products
mascara6 products
hand cream6 products
detangler5 products
around-eye cream4 products
hair spray4 products
CC cream4 products
glitter4 products
hand sanitizer3 products
3 products
toners/astringents3 products
body firming lotion3 products
setting powder/spray2 products
foot cleansing2 products
shaving cream2 products
nail polish1 products
hair removal waxes1 products
bubble bath1 products
tanning oil1 products
brow liner1 products
skin fading/lightener1 products
sunless tanning1 products

Use restrictions

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CONCERN REFERENCE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review Assessments
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Allergies/immunotoxicity

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CONCERN REFERENCE
Human any toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
One or more human case studies show significant immune or allergenic effectsOpen scientific literature

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Limited evidence of gastrointestinal or liver toxicityScorecard.org Toxicity Information
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Ecotoxicology

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CONCERN REFERENCE
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
50 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review Assessments

Persistence and bioaccumulation

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CONCERN REFERENCE
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • Open scientific/peer reviewed literature
  • ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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