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IODOPROPYNYL BUTYLCARBAMATE
Score:
Data: Fair
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (high) and Non-reproductive organ system toxicity (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| moisturizer with SPF | 55 products |
| body wash/cleanser | 35 products |
| foundation | 33 products |
| beach & sport sunscreen | 27 products |
| conditioner | 20 products |
| shampoo | 18 products |
| facial moisturizer/treatment | 17 products |
| body firming lotion | 14 products |
| styling gel/lotion | 11 products |
| makeup remover | 10 products |
| Facial Sun Care | 9 products |
| around-eye cream | 9 products |
| liquid hand soap | 9 products |
| concealer | 7 products |
| hair styling aide | 7 products |
| BB cream | 5 products |
| facial cleanser | 5 products |
| eye liner | 4 products |
| detangler | 4 products |
| mascara | 4 products |
| serums & essences | 4 products |
| CC cream | 3 products |
| moisturizer | 3 products |
| eye shadow | 3 products |
| hair treatment/serum | 3 products |
| styling mousse/foam | 2 products |
| brow liner | 2 products |
| hand cream | 1 products |
| baby wipes | 1 products |
| makeup with SPF | 1 products |
| foot moisturizer | 1 products |
| anti-aging | 1 products |
| after sun product | 1 products |
| eye makeup remover | 1 products |
| hair spray | 1 products |
Use restrictions
| Concern | Reference |
|---|---|
| Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR) | Cosmetic Ingredient Review Assessments |
| Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit) | Japan's Standards for Cosmetics |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | Cosmetic Ingredient Review Assessments |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Human any toxicant or allergen - strong evidence | Cosmetic Ingredient Review Assessments |
| One or more human case studies show significant immune or allergenic effects | Pazzaglia M, Tosti A 1999. Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate in a cosmetic cream. Contact Dermatitis. 1999 Nov;41(5):290. |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Limited evidence of gastrointestinal or liver toxicity | US EPA Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right to Know. Proposed and Final Rules. 59 Federal Register 1788 (Jan 12, 1994); 59 Federal Register 61432 (November 30, 1994). Summarized in Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion. http://www.epa.gov/tri/chemical/hazard_cx.htm |
| One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient) | EPA Toxic Release Inventory PBTs |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Ecotoxicology
| Concern | Reference |
|---|---|
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern | Reference |
|---|---|
| Safety assessment was based on related chemical | Cosmetic Ingredient Review Assessments |
| 50 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR) | Cosmetic Ingredient Review Assessments |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
- Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
- Pazzaglia M, Tosti A 1999. Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate in a cosmetic cream. Contact Dermatitis. 1999 Nov;41(5):290.
- US EPA Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right to Know. Proposed and Final Rules. 59 Federal Register 1788 (Jan 12, 1994); 59 Federal Register 61432 (November 30, 1994). Summarized in Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion. http://www.epa.gov/tri/chemical/hazard_cx.htm
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
- EWG VERIFIED products meet use restrictions and warnings based on EWG review of company data
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
