EWG Skin Deep® | What is IODOPROPYNYL BUTYLCARBAMATE

HOW WE DETERMINE SCORES Learn more About EWG VERIFIED™

Data: Fair

Iodopropynyl Butylcarbamate

This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.

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Other Concerns

Use restrictions (high), Persistence and bioaccumulation (moderate), and Non-reproductive organ system toxicity (low)

SYNONYMS

3-IODO-2-PROPYNYL BUTYLCARBAMATE, BUTYL-3-IODO-2-PROPYNYL ESTER CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYLCARBAMATE, BUTYLCARBAMIC ACID, 3-IODO-2-PROPYNYL ESTER, CARBAMIC ACID, BUTYL, 3IODO2PROPYNYL ESTER, CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYL ESTER, IDOPROPYNL BUTYLCARBAMATE, IODOPROPYL BUTYLCARBAMATE, IODOPROPYNL BUTYLCARBAMATE, IODOPROPYNYL BUTYLCARBAMATE, and IPBC

Unacceptable

Unacceptable: EWG VERIFIED products cannot contain this ingredient

Iodopropynyl butylcarbamate is used as a preservative in cosmetic formulations; it is acutely toxic by inhalation and should not be used in products that can be aerosolized or inhaled.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
MODERATE

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
HIGH

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

body wash/cleanser	102 products
foundation	66 products
hair treatment/serum	57 products
shampoo	51 products
mask	50 products
liquid hand soap	47 products
conditioner	42 products
exfoliant/scrub	40 products
hair styling aide	40 products
facial moisturizer/treatment	31 products
styling gel/lotion	30 products
concealer	29 products
moisturizer	28 products
eye liner	27 products
facial cleanser	26 products
daily use with SPF	22 products
eye shadow	20 products
makeup remover	19 products
serums & essences	17 products
hair color and bleaching	13 products
makeup primer	11 products
foot moisturizer	9 products
anti-aging	8 products
baby wipes	7 products
recreational sunscreen	7 products
styling mousse/foam	6 products
around-eye cream	6 products
hand cream	5 products
after sun product	5 products
eye makeup remover	5 products
mascara	5 products
CC cream	4 products
hair spray	4 products
hand sanitizer	3 products
glitter	3 products
toners/astringents	3 products
	2 products
foot cleansing	2 products
body firming lotion	2 products
setting powder/spray	2 products
brow liner	2 products
shaving cream	2 products
hair removal waxes	1 products
bubble bath	1 products
detangler	1 products
tanning oil	1 products
sunless tanning	1 products
body spray	1 products
skin fading/lightener	1 products
after shave	1 products

Use restrictions

CONCERN	REFERENCE
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)	Cosmetic Ingredient Review Assessments
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)	Japan's Standards for Cosmetics
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications	Cosmetic Ingredient Review Assessments

Allergies/immunotoxicity

CONCERN	REFERENCE
Human any toxicant or allergen - strong evidence	Cosmetic Ingredient Review Assessments
One or more human case studies show significant immune or allergenic effects	Open scientific literature

Persistence and bioaccumulation

CONCERN	REFERENCE
Persistent or bioaccumulative and moderate to high toxicity concern in humans	Open scientific literature
Not suspected to be persistent	Environment Canada Domestic Substance List
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Limited evidence of gastrointestinal or liver toxicity	Scorecard.org Toxicity Information
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)	EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Ecotoxicology

CONCERN	REFERENCE
Suspected to be an environmental toxin	Environment Canada Domestic Substance List

Data gaps

CONCERN	REFERENCE
Safety assessment was based on related chemical	Cosmetic Ingredient Review Assessments
50 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Informational

CONCERN	REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)	Cosmetic Ingredient Review Assessments

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
Open scientific/peer reviewed literature
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
ED (Environmental Defense). 2006. Scorecard _ The Pollution Information Site. http://www.scorecard.org.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

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Low Availability

Moderate Availability

High Availability