Menu Close Menu

Menu

IODOPROPYNYL BUTYLCARBAMATE

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high) and Non-reproductive organ system toxicity (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

Expand content Collapse content
body wash/cleanser51 products
moisturizer with SPF49 products
foundation34 products
shampoo24 products
conditioner24 products
beach & sport sunscreen23 products
facial moisturizer/treatment19 products
body firming lotion16 products
makeup remover15 products
styling gel/lotion13 products
hair styling aide13 products
liquid hand soap11 products
hair treatment/serum10 products
around-eye cream9 products
Facial Sun Care9 products
baby wipes8 products
moisturizer8 products
facial cleanser8 products
concealer7 products
eye shadow7 products
mask6 products
serums & essences6 products
BB cream5 products
detangler5 products
mascara5 products
eye liner4 products
CC cream3 products
styling mousse/foam2 products
after sun product2 products
eye makeup remover2 products
hair spray2 products
brow liner2 products
hand cream1 products
exfoliant/scrub1 products
makeup with SPF1 products
foot moisturizer1 products
beard care1 products
anti-aging1 products
sunless tanning1 products
after shave1 products

Use restrictions

Expand content Collapse content
Concern Reference
Violation of industry recommendations - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review Assessments
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsCosmetic Ingredient Review Assessments

Allergies/immunotoxicity

Expand content Collapse content
Concern Reference
Human any toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Study demonstrates allergic contact dermatitis of chemical in cosmetic creamPazzaglia M, Tosti A 1999. Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate in a cosmetic cream. Contact Dermatitis. 1999 Nov;41(5):290.

Organ system toxicity (non-reproductive)

Expand content Collapse content
Concern Reference
Limited evidence of gastrointestinal or liver toxicityUS EPA Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right to Know. Proposed and Final Rules. 59 Federal Register 1788 (Jan 12, 1994); 59 Federal Register 61432 (November 30, 1994). Summarized in Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion. http://www.epa.gov/tri/chemical/hazard_cx.htm
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Ecotoxicology

Expand content Collapse content
Concern Reference
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Expand content Collapse content
Concern Reference
Safety assessment was based on related chemicalCosmetic Ingredient Review Assessments
50 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

Expand content Collapse content
Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Not safe for use in products intended to be aerosolized, according to industry safety panel (Cosmetic Ingredient Review, CIR)Cosmetic Ingredient Review Assessments

Persistence and bioaccumulation

Expand content Collapse content
Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • Pazzaglia M, Tosti A 1999. Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate in a cosmetic cream. Contact Dermatitis. 1999 Nov;41(5):290.
  • US EPA Addition of Certain Chemicals; Toxic Chemical Release Reporting; Community Right to Know. Proposed and Final Rules. 59 Federal Register 1788 (Jan 12, 1994); 59 Federal Register 61432 (November 30, 1994). Summarized in Hazard Information on Toxic Chemicals Added to EPCRA Section 313 Under Chemical Expansion. http://www.epa.gov/tri/chemical/hazard_cx.htm
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.
  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer