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FD&C Yellow 5 (CI 19140)

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Neurotoxicity (moderate), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), and Contamination concerns (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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body wash/cleanser339 products
lipstick278 products
liquid hand soap267 products
conditioner196 products
shampoo192 products
bath oil/salts/soak173 products
eye shadow172 products
lip gloss168 products
brow liner161 products
eye liner155 products
bar soap108 products
fragrance for women102 products
moisturizer96 products
nail polish89 products
mask76 products
hand sanitizer74 products
exfoliant/scrub66 products
facial cleanser65 products
body spray57 products
facial moisturizer/treatment57 products
bronzer/highlighter56 products
hair styling aide56 products
concealer54 products
fragrance for men50 products
blush46 products
glitter46 products
sunless tanning42 products
lip balm40 products
hair treatment/serum37 products
after sun product34 products
styling gel/lotion30 products
bubble bath29 products
lip liner28 products
toothpaste27 products
mouthwash26 products
serums & essences24 products
makeup primer22 products
hair color and bleaching22 products
foundation21 products
lip balm with SPF21 products
around-eye cream18 products
toners/astringents18 products
body firming lotion15 products
setting powder/spray14 products
daily use with SPF12 products
after shave11 products
antiperspirant/deodorant11 products
mascara10 products
lip plumper9 products
hand cream8 products
foot cleansing7 products
antiperspirant/deodorant (men's)7 products
recreational sunscreen7 products
7 products
beard care7 products
anti-aging6 products
foot moisturizer6 products
detangler6 products
makeup remover6 products
facial powder4 products
styling mousse/foam4 products
hair spray4 products
cuticle treatment4 products
nail treatment3 products
foot odor control3 products
other eye makeup3 products
body oil2 products
hair-loss treatment2 products
hair relaxer2 products
shaving cream2 products
shaving cream (men's)2 products
damaged skin treatment2 products
beard oil2 products
tooth whitening1 products
polish remover1 products
hair removal waxes1 products
baby shampoo1 products
BB cream1 products
tanning oil1 products
baby oil1 products
baby lotion1 products

Contamination concerns

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Persistence and bioaccumulation

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Concern Reference
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List
Not suspected to be persistentEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as medium human health priorityEnvironment Canada Domestic Substance List
One or more animal studies show any effects at high doses (low dose studies may be unavailable for this ingredient)Open scientific literature
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Neurotoxicity

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Concern Reference
One or more human case studies show significant any effectsOpen scientific literature
One or more human case studies show possible any effectsOpen scientific literature
One or more animal studies show any effects at moderate dosesOpen scientific literature
One or more animal studies show any effects at high dosesOpen scientific literature

Allergies/immunotoxicity

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Concern Reference
Human any toxicant or allergen - moderate evidenceOpen scientific literature
One or more human case studies show possible any or allergenic effectsOpen scientific literature
One or more human case studies show equivocal any or allergenic effectsOpen scientific literature

Cancer

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Concern Reference
Cancer - limited evidenceOpen scientific literature
One or more in vitro tests on mammalian cells show positive mutation resultsOpen scientific literature
One or more in vitro tests on cells show inconclusive, but potentially positive mutation resultsOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsInt'l Agency for Research on Cancer (IARC) - Carcinogens
Not likely to be mutagenic in humansOpen scientific literature

Endocrine disruption

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Concern Reference
One or more studies show weak endocrine disruptionOpen scientific literature
Associated with endocrine disruptionOpen scientific literature

Developmental/reproductive toxicity

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Concern Reference
One or more animal studies show any effects at high dosesOpen scientific literature
any - weight of evidence unknown/unassessed/unreviewedOpen scientific literature

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmeticsFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Data gaps

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Concern Reference
370 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data Sources

  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Open scientific/peer reviewed literature
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met the program’s impurity restrictions based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer