EWG Skin Deep® | What is CI 42090 (FD&C Blue No. 1 or D&C Blue No. 4)

HOW WE DETERMINE SCORES Learn more About EWG VERIFIED™

Data: Fair

Ci 42090 (Fd&C Blue No. 1 Or D&C Blue No. 4)

^†This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
^†This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
^†This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
^†This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
^†Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

FIND PRODUCTS WITH THIS INGREDIENT

Other Concerns

Use restrictions (high), Neurotoxicity (low), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (moderate), and Contamination concerns (high)

SYNONYMS

-1-YLIDENE)-3-SULFO-, INNER SALT, DIAMMONIUM SALT, 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-, MONOSODIUM SALT, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]- MONOSODIUM SALT 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-1-NAPHTHALENESULFONATE CALCIUM, AKA205, AO1, BENZENEMETHANAMINIUM, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-3-SULFO-, INNER SALT, DISODIUM SALT, BENZENEMETHANAMINIUM, NETHYLN[4[[4[ETHYL[(3SULFOPHENYL)METHYL]AMINO]PHENYL](2SULFOPHENYL)METHYLENE]2,5CYCLOHEXADIEN1YLIDENE]3SULFO, HYDROXIDE, INNER SALT, DISODIUM SALT, BLUE 1, BLUE 4, C.I. ACID BLUE 9, DISODIUM SALT, CA LITHOL RED, CALCIUM, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-1-NAPHTHALENESULFONATE, CI 42090, CI 42090 (FD&C BLUE NO. 1 OR D&C BLUE NO. 4), D&C BLUE 4, D&C BLUE NO. 4, DIAMMONIUM SALT -1-YLIDENE)-3-SULFO-, INNER SALT, DIHYDROGEN (ETHYL)[4-[4-[ETHYL(3-SULPHONATOBENZYL)]AMINO]-2'-SULPHONATOBENZHYDRYLIDENE]CYCLOHEXA-2,5-DIEN-1-YLIDENE](3-SULPHONATOBENZYL)AMMONIUM, DISODIUM SALT, FD&C BLUE 1, FD&C BLUE NO. 1, FOOD BLUE 2, INNER SALT DIAMMONIUM SALT -1-YLIDENE)-3-SULFO-, JAPAN BLUE 1, LITHOL RED, CA, MONOSODIUM SALT 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-, N-ETHYL-N-(4-((4- ETHYL((3-SULFOPHENYL)METHYL)AMINO)PHENYL)(2-SULFOPHENYL)METHYLENE)-2,5-CYCLOHEXADIEN, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHY LENE]-2,5-CYCLOHEXADIEN-, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLE NE]-2,5-CYCLOHEXADIEN-, N-ETHYL-N-[4[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-3-SULFOBENZENENETHANAMINOM HYDROXIDE, INNER SALT, DISODIUM SALT, and SODIUM 2-[(2-HYDROXYNAPHTHYL)AZO]NAPHTHALENESULPHONATE

FD&C Blue 1 is a synthetic dye produced from petroleum; this dye is FDA-approved for use in food, pharmaceuticals and cosmetics.

Common concerns

See how this product scores for common concerns.

LOW

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
HIGH

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

body wash/cleanser	324 products
lipstick	252 products
liquid hand soap	222 products
nail polish	151 products
bath oil/salts/soak	149 products
shampoo	143 products
toothpaste	102 products
conditioner	100 products
eye shadow	95 products
lip gloss	91 products
mask	78 products
hand sanitizer	78 products
eye liner	73 products
mouthwash	70 products
fragrance for women	58 products
exfoliant/scrub	58 products
sunless tanning	58 products
facial cleanser	56 products
bar soap	53 products
brow liner	48 products
facial moisturizer/treatment	41 products
moisturizer	39 products
lip liner	37 products
fragrance for men	36 products
lip balm	32 products
hair styling aide	32 products
styling gel/lotion	30 products
bubble bath	29 products
after sun product	27 products
hair color and bleaching	26 products
hair treatment/serum	26 products
body spray	24 products
toners/astringents	24 products
shaving cream	22 products
serums & essences	22 products
blush	21 products
antiperspirant/deodorant (men's)	18 products
shaving cream (men's)	15 products
antiperspirant/deodorant	15 products
bronzer/highlighter	13 products
makeup primer	11 products
around-eye cream	10 products
setting powder/spray	10 products
body oil	10 products
after shave	9 products
body firming lotion	9 products
lip plumper	9 products
hand cream	8 products
makeup remover	8 products
	8 products
glitter	7 products
recreational sunscreen	7 products
tooth whitening	6 products
mascara	6 products
daily use with SPF	6 products
foot cleansing	5 products
concealer	5 products
lip balm with SPF	5 products
polish remover	4 products
foot moisturizer	4 products
baby bubble bath	4 products
beard care	4 products
nail treatment	3 products
muscle/joint soreness	3 products
hair spray	3 products
facial powder	3 products
other eye makeup	3 products
baby shampoo	2 products
beard cleanser	2 products
eye makeup remover	1 products
vapor rubs	1 products
hair-loss treatment	1 products
hair relaxer	1 products
oil controller	1 products
hair removal waxes	1 products
foot odor control	1 products
styling mousse/foam	1 products
BB cream	1 products
baby toothpaste	1 products
baby oil	1 products
damaged skin treatment	1 products

Contamination concerns

Chemical
ANILINE
CADMIUM (pyrophoric)

Use restrictions

CONCERN	REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	FDA Color Additive Status
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any	CosIng

Persistence and bioaccumulation

CONCERN	REFERENCE
Persistent or bioaccumulative and moderate to high toxicity concern in humans	Environment Canada Domestic Substance List
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Classified as medium human health priority	Environment Canada Domestic Substance List
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)	EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

CONCERN	REFERENCE
Limited evidence of any irritation	Open scientific literature

Multiple, additive exposure sources

CONCERN	REFERENCE
Used in food or as an additive with limited or no toxicity information available	Open scientific literature
Designated as safe for general or specific, limited use in food	FDA Everything Added to Food

Neurotoxicity

CONCERN	REFERENCE
One or more animal studies show any effects at moderate doses	Open scientific literature
One or more in vitro tests on mammalian cells demonstrate neurotoxicity	Open scientific literature

Endocrine disruption

CONCERN	REFERENCE
Associated with endocrine disruption	Open scientific literature

Cancer

CONCERN	REFERENCE
One or more in vitro tests on cells show inconclusive, but potentially positive mutation results	Open scientific literature
Not likely to be mutagenic in humans	Open scientific literature
Not likely to be carcinogenic in humans	Open scientific literature
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps	Int'l Agency for Research on Cancer (IARC) - Carcinogens

Informational

CONCERN	REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics	FDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration	CTFA International Cosmetic Ingredient Dictionary and Handbook

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Data gaps

CONCERN	REFERENCE
477 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Developmental/reproductive toxicity

CONCERN	REFERENCE
Not likely to be a reproductive or developmental toxin	Open scientific literature

FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Open scientific/peer reviewed literature
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability