EWG Skin Deep® | What is CI 42090 (FD&C Blue No. 1 or D&C Blue No. 4)

HOW WE DETERMINE SCORES Learn more About EWG VERIFIED®

Data: Fair

Ci 42090 (Fd&C Blue No. 1 Or D&C Blue No. 4)

This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

IMAGE SOURCE: PubChem

SEARCH PRODUCTS

FIND PRODUCTS WITH THIS INGREDIENT

Other Concerns

Use restrictions (high), Neurotoxicity (low), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (moderate), and Contamination concerns (high)

SYNONYMS

● -1-YLIDENE)-3-SULFO-, INNER SALT, DIAMMONIUM SALT

● 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-, MONOSODIUM SALT

● 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]- MONOSODIUM SALT 1-NAPHTHALENESULFONIC ACID

● 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-1-NAPHTHALENESULFONATE CALCIUM

● AKA205

● AO1

● BENZENEMETHANAMINIUM, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-3-SULFO-, INNER SALT, DISODIUM SALT

● BENZENEMETHANAMINIUM, NETHYLN[4[[4[ETHYL[(3SULFOPHENYL)METHYL]AMINO]PHENYL](2SULFOPHENYL)METHYLENE]2,5CYCLOHEXADIEN1YLIDENE]3SULFO, HYDROXIDE, INNER SALT, DISODIUM SALT

● BLUE 1

● BLUE 4

● C.I. ACID BLUE 9, DISODIUM SALT

● CA LITHOL RED

● CALCIUM, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-1-NAPHTHALENESULFONATE

● CI 42090

● CI 42090 (FD&C BLUE NO. 1 OR D&C BLUE NO. 4)

● D&C BLUE 4

● D&C BLUE NO. 4

● DIAMMONIUM SALT -1-YLIDENE)-3-SULFO-, INNER SALT

● DIHYDROGEN (ETHYL)[4-[4-[ETHYL(3-SULPHONATOBENZYL)]AMINO]-2'-SULPHONATOBENZHYDRYLIDENE]CYCLOHEXA-2,5-DIEN-1-YLIDENE](3-SULPHONATOBENZYL)AMMONIUM, DISODIUM SALT

● FD&C BLUE 1

● FD&C BLUE NO. 1

● FOOD BLUE 2

● INNER SALT DIAMMONIUM SALT -1-YLIDENE)-3-SULFO-

● JAPAN BLUE 1

● LITHOL RED, CA

● MONOSODIUM SALT 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-

● N-ETHYL-N-(4-((4- ETHYL((3-SULFOPHENYL)METHYL)AMINO)PHENYL)(2-SULFOPHENYL)METHYLENE)-2,5-CYCLOHEXADIEN

● N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHY LENE]-2,5-CYCLOHEXADIEN-

● N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLE NE]-2,5-CYCLOHEXADIEN-

● N-ETHYL-N-[4[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-3-SULFOBENZENENETHANAMINOM HYDROXIDE, INNER SALT, DISODIUM SALT

● SODIUM 2-[(2-HYDROXYNAPHTHYL)AZO]NAPHTHALENESULPHONATE

Restricted - Unaccpetable

The score of this ingredient can vary from Restricted to Unacceptable based on the method of product consumption. For instance, when used in aerosol-based products, this ingredient may pose a risk to respiratory health, leading to a higher score

Click here for more information about ingredient scores

FD&C Blue 1 is a synthetic dye produced from petroleum; this dye is FDA-approved for use in food, pharmaceuticals and cosmetics.

Common concerns

See how this product scores for common concerns.

MODERATE

Cancer
LOW

Allergies & Immunotoxicity
LOW

Developmental and Reproductive Toxicity
HIGH

Use Restrictions

Ingredient concerns

CONCERNS
DATA SOURCES

Products with this Ingredient

body wash/cleanser	320 products
lipstick	258 products
liquid hand soap	213 products
shampoo	190 products
bath oil/salts/soak	162 products
toothpaste	145 products
eye shadow	126 products
conditioner	122 products
eye liner	108 products
nail polish	93 products
exfoliant/scrub	84 products
lip gloss	84 products
mouthwash	82 products
mask	78 products
sunless tanning	70 products
hand sanitizer	68 products
fragrance for women	61 products
facial cleanser	60 products
brow liner	58 products
bar soap	50 products
blush	46 products
lip liner	39 products
facial moisturizer/treatment	39 products
moisturizer	36 products
hair styling aide	36 products
styling gel/lotion	35 products
lip balm	35 products
fragrance for men	33 products
antiperspirant/deodorant	28 products
antiperspirant/deodorant (men's)	25 products
bubble bath	25 products
hair treatment/serum	25 products
toners/astringents	24 products
after sun product	23 products
serums & essences	23 products
body spray	20 products
shaving cream	20 products
hair color and bleaching	19 products
setting powder/spray	19 products
around-eye cream	15 products
shaving cream (men's)	13 products
hand cream	13 products
bronzer/highlighter	13 products
after shave	10 products
makeup primer	10 products
polish remover	10 products
body oil	10 products
lip plumper	10 products
makeup remover	9 products
recreational sunscreen	9 products
tooth whitening	7 products
mascara	7 products
	7 products
concealer	5 products
lip balm with SPF	5 products
hair spray	4 products
foot moisturizer	4 products
styling mousse/foam	4 products
nail treatment	3 products
muscle/joint soreness	3 products
body firming lotion	3 products
facial powder	3 products
other eye makeup	3 products
baby bubble bath	3 products
beard care	3 products
daily use with SPF	2 products
baby toothpaste	2 products
baby oil	2 products
beard cleanser	2 products
foundation	1 products
glitter	1 products
vapor rubs	1 products
hair-loss treatment	1 products
detangler	1 products
hair removal waxes	1 products
eyelash glue	1 products
tanning oil	1 products
baby shampoo	1 products

Contamination concerns

Chemical
ANILINE
CADMIUM (pyrophoric)

Use restrictions

CONCERN	REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only	FDA Color Additive Status
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any	CosIng

Persistence and bioaccumulation

CONCERN	REFERENCE
Persistent or bioaccumulative and moderate to high toxicity concern in humans	Environment Canada Domestic Substance List
Not suspected to be bioaccumulative	Environment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

CONCERN	REFERENCE
Classified as medium human health priority	Environment Canada Domestic Substance List
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)	EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmful	Environment Canada Domestic Substance List

Cancer

CONCERN	REFERENCE
Limited evidence of carcinogenicity	Open scientific literature
One or more in vitro tests on cells show inconclusive, but potentially positive mutation results	Open scientific literature
Not likely to be mutagenic in humans	Open scientific literature
Not likely to be carcinogenic in humans	Open scientific literature
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps	Int'l Agency for Research on Cancer (IARC) - Carcinogens

Irritation (skin, eyes, or lungs)

CONCERN	REFERENCE
Limited evidence of any irritation	Open scientific literature

Multiple, additive exposure sources

CONCERN	REFERENCE
Used in food or as an additive with limited or no toxicity information available	Open scientific literature
Designated as safe for general or specific, limited use in food	FDA Everything Added to Food

Neurotoxicity

CONCERN	REFERENCE
One or more animal studies show any effects at moderate doses	Open scientific literature
One or more in vitro tests on mammalian cells demonstrate neurotoxicity	Open scientific literature

Endocrine disruption

CONCERN	REFERENCE
Associated with endocrine disruption	Open scientific literature

Informational

CONCERN	REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics	FDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration	CTFA International Cosmetic Ingredient Dictionary and Handbook

Ecotoxicology

CONCERN	REFERENCE
Not suspected to be an environmental toxin	Environment Canada Domestic Substance List

Data gaps

CONCERN	REFERENCE
477 studies in PubMed science library may include information on the toxicity of this chemical	NLM PubMed

Developmental/reproductive toxicity

CONCERN	REFERENCE
Not likely to be a reproductive or developmental toxin	Open scientific literature

FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
Open scientific/peer reviewed literature
IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED^® mark means a product meets EWG’s strictest criteria for transparency and health.

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST

Low Availability

Moderate Availability

High Availability