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Data: Fair

Ci 42090 (Fd&C Blue No. 1 Or D&C Blue No. 4)

  • This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
  • This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
  • This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
  • This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
  • Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.

IMAGE SOURCE: PubChem

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Other Concerns

Use restrictions (high), Neurotoxicity (low), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (moderate), and Contamination concerns (high)

SYNONYMS

-1-YLIDENE)-3-SULFO-, INNER SALT, DIAMMONIUM SALT, 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-, MONOSODIUM SALT, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]- MONOSODIUM SALT 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-1-NAPHTHALENESULFONATE CALCIUM, AKA205, AO1, BENZENEMETHANAMINIUM, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-3-SULFO-, INNER SALT, DISODIUM SALT, BENZENEMETHANAMINIUM, NETHYLN[4[[4[ETHYL[(3SULFOPHENYL)METHYL]AMINO]PHENYL](2SULFOPHENYL)METHYLENE]2,5CYCLOHEXADIEN1YLIDENE]3SULFO, HYDROXIDE, INNER SALT, DISODIUM SALT, BLUE 1, BLUE 4, C.I. ACID BLUE 9, DISODIUM SALT, CA LITHOL RED, CALCIUM, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-1-NAPHTHALENESULFONATE, CI 42090, CI 42090 (FD&C BLUE NO. 1 OR D&C BLUE NO. 4), D&C BLUE 4, D&C BLUE NO. 4, DIAMMONIUM SALT -1-YLIDENE)-3-SULFO-, INNER SALT, DIHYDROGEN (ETHYL)[4-[4-[ETHYL(3-SULPHONATOBENZYL)]AMINO]-2'-SULPHONATOBENZHYDRYLIDENE]CYCLOHEXA-2,5-DIEN-1-YLIDENE](3-SULPHONATOBENZYL)AMMONIUM, DISODIUM SALT, FD&C BLUE 1, FD&C BLUE NO. 1, FOOD BLUE 2, INNER SALT DIAMMONIUM SALT -1-YLIDENE)-3-SULFO-, JAPAN BLUE 1, LITHOL RED, CA, MONOSODIUM SALT 1-NAPHTHALENESULFONIC ACID, 2-[(2-HYDROXY-1-NAPHTHALENYL)AZO]-, N-ETHYL-N-(4-((4- ETHYL((3-SULFOPHENYL)METHYL)AMINO)PHENYL)(2-SULFOPHENYL)METHYLENE)-2,5-CYCLOHEXADIEN, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHY LENE]-2,5-CYCLOHEXADIEN-, N-ETHYL-N-[4-[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLE NE]-2,5-CYCLOHEXADIEN-, N-ETHYL-N-[4[[4-[ETHYL[(3-SULFOPHENYL)METHYL]AMINO]PHENYL](2-SULFOPHENYL)METHYLENE]-2,5-CYCLOHEXADIEN-1-YLIDENE]-3-SULFOBENZENENETHANAMINOM HYDROXIDE, INNER SALT, DISODIUM SALT, and SODIUM 2-[(2-HYDROXYNAPHTHYL)AZO]NAPHTHALENESULPHONATE

FD&C Blue 1 is a synthetic dye produced from petroleum; this dye is FDA-approved for use in food, pharmaceuticals and cosmetics.

Common concerns

See how this product scores for common concerns.

  • LOW
    Cancer
  • LOW
    Allergies & Immunotoxicity
  • LOW
    Developmental and Reingredientive Toxicity
  • HIGH
    Use Restrictions

Ingredient concerns

  • CONCERNS
  • DATA SOURCES

Products with this Ingredient

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body wash/cleanser319 products
lipstick242 products
liquid hand soap214 products
bath oil/salts/soak158 products
nail polish149 products
shampoo145 products
toothpaste99 products
conditioner97 products
eye shadow94 products
lip gloss89 products
hand sanitizer78 products
mask77 products
mouthwash70 products
fragrance for women60 products
sunless tanning57 products
facial cleanser56 products
exfoliant/scrub53 products
bar soap51 products
brow liner48 products
facial moisturizer/treatment41 products
moisturizer40 products
fragrance for men39 products
lip liner37 products
eye liner34 products
hair styling aide33 products
lip balm32 products
styling gel/lotion31 products
bubble bath29 products
hair color and bleaching26 products
after sun product25 products
hair treatment/serum25 products
body spray24 products
toners/astringents24 products
shaving cream22 products
blush21 products
serums & essences20 products
shaving cream (men's)16 products
antiperspirant/deodorant (men's)16 products
antiperspirant/deodorant15 products
bronzer/highlighter11 products
makeup primer11 products
setting powder/spray10 products
body oil10 products
around-eye cream9 products
after shave9 products
hand cream8 products
makeup remover8 products
lip plumper8 products
glitter7 products
body firming lotion7 products
recreational sunscreen7 products
7 products
mascara6 products
daily use with SPF6 products
tooth whitening5 products
foot cleansing5 products
concealer5 products
foot moisturizer4 products
baby bubble bath4 products
beard care4 products
nail treatment3 products
muscle/joint soreness3 products
polish remover3 products
hair spray3 products
facial powder3 products
other eye makeup3 products
baby shampoo2 products
beard cleanser2 products
eye makeup remover1 products
vapor rubs1 products
hair-loss treatment1 products
hair relaxer1 products
oil controller1 products
hair removal waxes1 products
foot odor control1 products
styling mousse/foam1 products
body art1 products
BB cream1 products
baby toothpaste1 products
tanning oil1 products
baby oil1 products
damaged skin treatment1 products

Contamination concerns

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Use restrictions

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CONCERN REFERENCE
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use onlyFDA Color Additive Status
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - anyCosIng

Persistence and bioaccumulation

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CONCERN REFERENCE
Persistent or bioaccumulative and moderate to high toxicity concern in humansEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

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CONCERN REFERENCE
Classified as medium human health priorityEnvironment Canada Domestic Substance List
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

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CONCERN REFERENCE
Limited evidence of any irritationOpen scientific literature

Multiple, additive exposure sources

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CONCERN REFERENCE
Used in food or as an additive with limited or no toxicity information availableOpen scientific literature
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Neurotoxicity

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CONCERN REFERENCE
One or more animal studies show any effects at moderate dosesOpen scientific literature
One or more in vitro tests on mammalian cells demonstrate neurotoxicityOpen scientific literature

Endocrine disruption

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CONCERN REFERENCE
Associated with endocrine disruptionOpen scientific literature

Cancer

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CONCERN REFERENCE
One or more in vitro tests on cells show inconclusive, but potentially positive mutation resultsOpen scientific literature
Not likely to be mutagenic in humansOpen scientific literature
Not likely to be carcinogenic in humansOpen scientific literature
Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gapsInt'l Agency for Research on Cancer (IARC) - Carcinogens

Informational

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CONCERN REFERENCE
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmeticsFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Ecotoxicology

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CONCERN REFERENCE
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

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CONCERN REFERENCE
477 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Developmental/reproductive toxicity

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CONCERN REFERENCE
Not likely to be a reproductive or developmental toxinOpen scientific literature
  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
  • Open scientific/peer reviewed literature
  • FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
  • IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

Understanding scores

Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.

Every product and ingredient in Skin Deep gets a two-part score – one for hazard and one for data availability. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating.

HOW WE DETERMINE SCORES

Hazard score

The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. The EWG VERIFIED™ mark means a product meets EWG’s strictest criteria for transparency and health.

Score legend

Data availability

The Skin Deep data availability rating reflects the number of scientific studies about the product or ingredient in the published scientific literature.

NONE LIMITED FAIR GOOD ROBUST
Low Availability
Moderate Availability
High Availability

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