CI 42090 (FD&C Blue No. 1 or D&C Blue No. 4)
- Other Concerns
- About the Chemical
Use restrictions (high), Neurotoxicity (low), Endocrine disruption (low), Persistence and bioaccumulation (moderate), Non-reproductive organ system toxicity (moderate), Multiple, additive exposure sources (low), Irritation (skin, eyes, or lungs) (moderate), and Contamination concerns (high)
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
|body wash/cleanser||391 products|
|liquid hand soap||227 products|
|bath oil/salts/soak||179 products|
|nail polish||116 products|
|lip gloss||112 products|
|eye liner||109 products|
|eye shadow||102 products|
|hand sanitizer||80 products|
|bar soap||69 products|
|facial cleanser||66 products|
|fragrance for women||59 products|
|brow liner||54 products|
|facial moisturizer/treatment||43 products|
|sunless tanning||41 products|
|fragrance for men||40 products|
|hair styling aide||39 products|
|styling gel/lotion||38 products|
|bubble bath||37 products|
|after sun product||34 products|
|body spray||33 products|
|shaving cream||32 products|
|lip balm||31 products|
|antiperspirant/deodorant (men's)||29 products|
|hair treatment/serum||27 products|
|hair color and bleaching||26 products|
|shaving cream (men's)||19 products|
|lip liner||18 products|
|serums & essences||18 products|
|makeup primer||14 products|
|after shave||13 products|
|makeup remover||12 products|
|around-eye cream||11 products|
|body firming lotion||10 products|
|setting powder/spray||9 products|
|tooth whitening||8 products|
|hand cream||8 products|
|lip plumper||8 products|
|foot cleansing||7 products|
|recreational sunscreen||7 products|
|polish remover||6 products|
|daily use with SPF||6 products|
|foot moisturizer||5 products|
|hair-loss treatment||4 products|
|baby bubble bath||4 products|
|beard care||4 products|
|hair spray||3 products|
|facial powder||3 products|
|other eye makeup||3 products|
|beard cleanser||3 products|
|nail treatment||2 products|
|muscle/joint soreness||2 products|
|baby shampoo||2 products|
|eye makeup remover||1 products|
|vapor rubs||1 products|
|hair relaxer||1 products|
|oil controller||1 products|
|foot odor control||1 products|
|styling mousse/foam||1 products|
|cuticle treatment||1 products|
|body art||1 products|
|BB cream||1 products|
|baby toothpaste||1 products|
|body oil||1 products|
|tanning oil||1 products|
|baby oil||1 products|
|damaged skin treatment||1 products|
|Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only||FDA Color Additive Status|
|Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - any||CosIng|
Persistence and bioaccumulation
|Persistent or bioaccumulative and moderate to high toxicity concern in humans||Environment Canada Domestic Substance List|
|Not suspected to be bioaccumulative||Environment Canada Domestic Substance List|
Organ system toxicity (non-reproductive)
|Classified as medium human health priority||Environment Canada Domestic Substance List|
|One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)||EPA Toxic Release Inventory PBTs|
|Classified as not expected to be potentially toxic or harmful||Environment Canada Domestic Substance List|
Irritation (skin, eyes, or lungs)
|Limited evidence of any irritation||Open scientific literature|
Multiple, additive exposure sources
|Used in food or as an additive with limited or no toxicity information available||Open scientific literature|
|Designated as safe for general or specific, limited use in food||FDA Everything Added to Food|
|One or more animal studies show any effects at moderate doses||Open scientific literature|
|One or more in vitro tests on mammalian cells demonstrate neurotoxicity||Open scientific literature|
|Associated with endocrine disruption||Open scientific literature|
|One or more in vitro tests on cells show inconclusive, but potentially positive mutation results||Open scientific literature|
|Not likely to be mutagenic in humans||Open scientific literature|
|Not likely to be carcinogenic in humans||Open scientific literature|
|Limited or incomplete evidence of cancer according to safety/hazard data – government assessment cannot classify as human carcinogen due to data gaps||Int'l Agency for Research on Cancer (IARC) - Carcinogens|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics||FDA Color Additive Status|
|Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration||CTFA International Cosmetic Ingredient Dictionary and Handbook|
|Not suspected to be an environmental toxin||Environment Canada Domestic Substance List|
|477 studies in PubMed science library may include information on the toxicity of this chemical||NLM PubMed|
|Not likely to be a reproductive or developmental toxin||Open scientific literature|
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
- Open scientific/peer reviewed literature
- FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
- IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99 (a total of 935 agents, mixtures and exposures).
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
- This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
- This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
- Products with the EWG VERIFIED mark have met the program’s impurity and use restrictions based on EWG's review of the company's data.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer