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Ext. D&C Violet No. 2 (CI 60730)

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (high), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (low)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is MODERATE

Products with this Ingredient

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fragrance for women32 products
liquid hand soap31 products
shampoo22 products
fragrance for men15 products
body wash/cleanser14 products
conditioner12 products
hair treatment/serum9 products
facial moisturizer/treatment8 products
facial cleanser7 products
hair color and bleaching5 products
nail polish5 products
styling gel/lotion4 products
polish remover4 products
mask4 products
hair styling aide4 products
moisturizer4 products
exfoliant/scrub3 products
hand sanitizer2 products
sunless tanning2 products
foot moisturizer1 products
shaving cream1 products
bubble bath1 products
body spray1 products
after shave1 products
anti-aging1 products
oil controller1 products
serums & essences1 products
baby shampoo1 products
moisturizer with SPF1 products
makeup remover1 products

Use restrictions

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Concern Reference
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use onlyFDA Color Additive Status
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualificationsIJT 20(S3):1-6, 2001

Allergies/immunotoxicity

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Concern Reference
Human skin toxicant or allergen - strong evidenceEWG Assessment of Open Scientific Literature
Testing was inadequate to exclude the posibility for dermal sensitizaton.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.

Organ system toxicity (non-reproductive)

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Concern Reference
Potential impacts on blood clotting observed in animal testing.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Cancer

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Concern Reference
Cancer - limited evidenceIJT 20(S3):1-6, 2001
Cancer - limited evidenceEWG Assessment of Open Scientific Literature
Genotoxicity reprorted in vitro tests.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.

Irritation (skin, eyes, or lungs)

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Concern Reference
Causes serious eye damage.European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6
Eye irritation reported from limited animal testing.European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.

Data gaps

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Concern Reference
2 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics: external use onlyFDA Color Additive Status
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug AdministrationCTFA International Cosmetic Ingredient Dictionary and Handbook

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
  • IJT 20(S3):1-6, 2001
  • EWG Assessment of Open Scientific Literature
  • European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.

About this Ingredient's Score Range

  • This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
  • This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
  • This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
  • This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

ABOUT EWG VERIFIED™

Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer