Ext. D&C Violet No. 2 (CI 60730)
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (high), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (low)
Cancer 

Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity 

Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity 

Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
liquid hand soap | 44 products |
fragrance for women | 36 products |
shampoo | 24 products |
fragrance for men | 19 products |
body wash/cleanser | 17 products |
conditioner | 13 products |
hair treatment/serum | 9 products |
facial moisturizer/treatment | 8 products |
hair color and bleaching | 8 products |
facial cleanser | 7 products |
mask | 6 products |
hand sanitizer | 6 products |
polish remover | 5 products |
hair styling aide | 5 products |
nail polish | 5 products |
styling gel/lotion | 4 products |
moisturizer | 4 products |
exfoliant/scrub | 3 products |
serums & essences | 2 products |
sunless tanning | 2 products |
foot moisturizer | 1 products |
shaving cream | 1 products |
bubble bath | 1 products |
styling mousse/foam | 1 products |
1 products | |
makeup primer | 1 products |
after shave | 1 products |
anti-aging | 1 products |
oil controller | 1 products |
detangler | 1 products |
baby shampoo | 1 products |
moisturizer with SPF | 1 products |
bath oil/salts/soak | 1 products |
makeup remover | 1 products |
Use restrictions
Concern | Reference |
---|---|
Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only | FDA Color Additive Status |
Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IJT 20(S3):1-6, 2001 |
Allergies/immunotoxicity
Concern | Reference |
---|---|
Human skin toxicant or allergen - strong evidence | EWG Assessment of Open Scientific Literature |
Testing was inadequate to exclude the posibility for dermal sensitizaton. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Organ system toxicity (non-reproductive)
Concern | Reference |
---|---|
Potential impacts on blood clotting observed in animal testing. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Cancer
Concern | Reference |
---|---|
Cancer - limited evidence | IJT 20(S3):1-6, 2001 |
Cancer - limited evidence | EWG Assessment of Open Scientific Literature |
Genotoxicity reprorted in vitro tests. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Irritation (skin, eyes, or lungs)
Concern | Reference |
---|---|
Causes serious eye damage. | European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6 |
Eye irritation reported from limited animal testing. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Data gaps
Concern | Reference |
---|---|
2 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Ecotoxicology
Concern | Reference |
---|---|
Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Informational
Concern | Reference |
---|---|
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics: external use only | FDA Color Additive Status |
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration | CTFA International Cosmetic Ingredient Dictionary and Handbook |
Persistence and bioaccumulation
Concern | Reference |
---|---|
Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- IJT 20(S3):1-6, 2001
- EWG Assessment of Open Scientific Literature
- European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
- This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
- This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
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