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Ext. D&C Violet No. 2 (CI 60730)
Score:
Data: Limited
- Other Concerns
- Functions
- About the Chemical
- Synonyms
-
Use restrictions (high), Non-reproductive organ system toxicity (moderate), and Irritation (skin, eyes, or lungs) (low)
Cancer 
Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments.
Developmental & Reproductive Toxicity
Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children.
Allergies & Immunotoxicity
Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body.
Products with this Ingredient
| fragrance for women | 28 products |
| liquid hand soap | 24 products |
| shampoo | 21 products |
| fragrance for men | 13 products |
| body wash/cleanser | 12 products |
| conditioner | 12 products |
| hair treatment/serum | 9 products |
| facial moisturizer/treatment | 8 products |
| facial cleanser | 7 products |
| hair color and bleaching | 4 products |
| styling gel/lotion | 4 products |
| mask | 4 products |
| moisturizer | 4 products |
| nail polish | 4 products |
| polish remover | 4 products |
| hair styling aide | 4 products |
| exfoliant/scrub | 3 products |
| sunless tanning | 2 products |
| hand sanitizer | 2 products |
| after shave | 1 products |
| foot moisturizer | 1 products |
| anti-aging | 1 products |
| bubble bath | 1 products |
| baby shampoo | 1 products |
| makeup remover | 1 products |
| oil controller | 1 products |
| serums & essences | 1 products |
| body spray | 1 products |
| shaving cream | 1 products |
| moisturizer with SPF | 1 products |
Use restrictions
| Concern | Reference |
|---|---|
| Violation of government restrictions - Restricted in cosmetics; use, concentration, or manufacturing restrictions - Color additive approved by FDA for use in cosmetics: external use only | FDA Color Additive Status |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications | IJT 20(S3):1-6, 2001 |
Allergies/immunotoxicity
| Concern | Reference |
|---|---|
| Human skin toxicant or allergen - strong evidence | EWG Assessment of Open Scientific Literature |
| Testing was inadequate to exclude the posibility for dermal sensitizaton. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Organ system toxicity (non-reproductive)
| Concern | Reference |
|---|---|
| Potential impacts on blood clotting observed in animal testing. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Cancer
| Concern | Reference |
|---|---|
| Cancer - limited evidence | IJT 20(S3):1-6, 2001 |
| Cancer - limited evidence | EWG Assessment of Open Scientific Literature |
| Genotoxicity reprorted in vitro tests. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Irritation (skin, eyes, or lungs)
| Concern | Reference |
|---|---|
| Causes serious eye damage. | European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6 |
| Eye irritation reported from limited animal testing. | European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63. |
Data gaps
| Concern | Reference |
|---|---|
| 2 studies in PubMed science library may include information on the toxicity of this chemical | NLM PubMed |
Ecotoxicology
| Concern | Reference |
|---|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Informational
| Concern | Reference |
|---|---|
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color additive approved by FDA for use in cosmetics: external use only | FDA Color Additive Status |
| Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - Color Additives - Batch Certified by the U.S. Food and Drug Administration | CTFA International Cosmetic Ingredient Dictionary and Handbook |
Persistence and bioaccumulation
| Concern | Reference |
|---|---|
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Data Sources
- FDA (U.S. Food and Drug Administration) 2006. Center for Food Safety and Applied Nutrition. Color Additive Status List. September 2006.
- IJT 20(S3):1-6, 2001
- EWG Assessment of Open Scientific Literature
- European Commission, Scientific Committee on Consumer Safety (SCCS) 2013. Opinion on Acid Violet 43 COLIPA n° C63.
- EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
- European Chemicals Agency (ECHA) 2018. GHS Data from ECHA Website. Appears as: chemical_names: Sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate; sodium 2-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-5-methylbenzene-1-sulfonate; Acid Violet 43; Benzenesulfonic acid, 2-((9,10-dihydro-4-hydroxy-9,10-dio; cas_numbers: 4430-18-6
- NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
- CTFA (Cosmetic, Toiletry and Fragrance Association). 2006. International Cosmetic Ingredient Dictionary and Handbook, 11th Edition. Color Additive Information. Washington, DC.
- This ingredient’s score is higher if used in products intended for damaged skin due to increased risk of absorption.
- This ingredient’s score is higher if used in products intended for use around mouth due to increased risk of ingestion and absorption.
- This ingredient’s score is higher if used in products intended for use on lips due to increased risk of ingestion and absorption.
- This ingredient’s score is higher if used in products intended for use around the eyes due to increased risk of absorption.
- Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.
ABOUT THE SKIN DEEP® RATINGS
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer
ABOUT EWG VERIFIED™
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer
