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ETHYLHEXYLGLYCERIN

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate), Ecotoxicology (low), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation429 products
lipstick358 products
mask289 products
facial moisturizer/treatment268 products
serums & essences216 products
eye shadow214 products
moisturizer with SPF181 products
conditioner179 products
moisturizer165 products
beach & sport sunscreen165 products
bronzer/highlighter145 products
concealer137 products
facial cleanser104 products
facial powder98 products
shampoo91 products
blush78 products
body wash/cleanser66 products
eye liner57 products
mascara57 products
brow liner52 products
makeup primer50 products
lip gloss49 products
around-eye cream47 products
exfoliant/scrub44 products
hair styling aide43 products
hair treatment/serum41 products
toners/astringents40 products
antiperspirant/deodorant35 products
body firming lotion35 products
styling gel/lotion34 products
CC cream31 products
makeup remover29 products
hand cream28 products
anti-aging22 products
baby sunscreen20 products
BB cream20 products
hair color and bleaching19 products
baby shampoo16 products
baby soap16 products
shaving cream16 products
Facial Sun Care13 products
lip balm12 products
baby lotion11 products
makeup with SPF10 products
detangler10 products
liquid hand soap10 products
styling mousse/foam9 products
shaving cream (men's)8 products
hair spray8 products
after shave7 products
sunless tanning7 products
bubble bath7 products
baby bubble bath6 products
other eye makeup6 products
foot moisturizer5 products
lip plumper4 products
beard care3 products
body spray3 products
oil controller3 products
antiperspirant/deodorant (men's)3 products
after sun product3 products
eye makeup remover2 products
bath oil/salts/soak2 products
nail treatment2 products
eyelash glue2 products
hand sanitizer2 products
glitter2 products
lip balm with SPF2 products
beard oil1 products
nail glue1 products
fragrance for men1 products
foot odor control1 products
lip liner1 products
vapor rubs1 products
other men's products1 products
Oils & Serums1 products
skin fading/lightener1 products
body oil1 products
bar soap1 products
muscle/joint soreness1 products
baby wipes1 products
cuticle treatment1 products
diaper cream1 products
baby oil1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling
Harmonized classification: this substance causes serious eye damage.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
Severe eye damage observed in animal testing.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
Classified as a mild skin irritant based on animal tests.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of eye toxicityCPS&Q - Classification & Labelling
Liver effects observed at low doses in repeat-dose studies in rats.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Allergies/immunotoxicity

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Concern Reference
Dermal sensitization has been reported in several human studies. Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
Contact dermatitis reported in human case reports.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Ecotoxicology

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Concern Reference
Harmonized classification: this substance is harmful to aquatic life with long lasting effects.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412

Data gaps

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Concern Reference
9 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 32 (S3): 5-21, 2013

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
  • Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • IJT 32 (S3): 5-21, 2013

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