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ETHYLHEXYLGLYCERIN

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate), Ecotoxicology (low), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation509 products
lipstick412 products
mask320 products
facial moisturizer/treatment308 products
eye shadow267 products
serums & essences239 products
concealer206 products
bronzer/highlighter199 products
conditioner193 products
moisturizer183 products
moisturizer with SPF176 products
beach & sport sunscreen135 products
facial cleanser118 products
facial powder106 products
blush99 products
shampoo96 products
eye liner92 products
brow liner73 products
mascara71 products
makeup primer70 products
body wash/cleanser66 products
lip gloss66 products
toners/astringents54 products
around-eye cream54 products
exfoliant/scrub50 products
hair styling aide50 products
hair treatment/serum46 products
makeup remover39 products
styling gel/lotion37 products
antiperspirant/deodorant34 products
hand cream32 products
CC cream30 products
body firming lotion29 products
hair color and bleaching29 products
anti-aging22 products
BB cream19 products
shaving cream18 products
eyelash glue17 products
baby shampoo15 products
baby soap14 products
baby lotion14 products
baby sunscreen13 products
lip balm13 products
liquid hand soap11 products
styling mousse/foam11 products
hair spray9 products
bubble bath9 products
detangler8 products
shaving cream (men's)8 products
other eye makeup6 products
baby bubble bath6 products
beard care6 products
foot moisturizer6 products
sunless tanning6 products
after shave6 products
lip plumper5 products
eye makeup remover5 products
after sun product5 products
antiperspirant/deodorant (men's)5 products
glitter4 products
body spray4 products
baby wipes3 products
bath oil/salts/soak3 products
oil controller3 products
damaged skin treatment3 products
3 products
makeup with SPF2 products
hand sanitizer2 products
lip balm with SPF2 products
cuticle treatment2 products
diaper cream2 products
muscle/joint soreness2 products
nail treatment1 products
foot cleansing1 products
baby oil1 products
bar soap1 products
foot odor control1 products
body oil1 products
vapor rubs1 products
nail glue1 products
fragrance for men1 products
lip liner1 products
other men's products1 products
beard oil1 products
body art1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling
Harmonized classification: this substance causes serious eye damage.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
Severe eye damage observed in animal testing.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
Classified as a mild skin irritant based on animal tests.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of eye toxicityCPS&Q - Classification & Labelling
Liver effects observed at low doses in repeat-dose studies in rats.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Allergies/immunotoxicity

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Concern Reference
Dermal sensitization has been reported in several human studies. Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
Contact dermatitis reported in human case reports.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Ecotoxicology

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Concern Reference
Harmonized classification: this substance is harmful to aquatic life with long lasting effects.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412

Data gaps

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Concern Reference
9 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 32 (S3): 5-21, 2013

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
  • Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • IJT 32 (S3): 5-21, 2013

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