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ETHYLHEXYLGLYCERIN

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate), Ecotoxicology (low), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation663 products
lipstick445 products
facial moisturizer/treatment398 products
mask371 products
serums & essences314 products
eye shadow304 products
moisturizer256 products
conditioner246 products
concealer245 products
bronzer/highlighter232 products
moisturizer with SPF221 products
facial cleanser173 products
beach & sport sunscreen169 products
shampoo121 products
blush116 products
eye liner114 products
facial powder107 products
body wash/cleanser102 products
brow liner102 products
makeup primer96 products
mascara94 products
hair styling aide94 products
exfoliant/scrub83 products
around-eye cream83 products
body firming lotion80 products
toners/astringents78 products
lip gloss78 products
hair treatment/serum68 products
styling gel/lotion55 products
hand cream48 products
antiperspirant/deodorant46 products
makeup remover43 products
CC cream38 products
anti-aging36 products
baby lotion31 products
BB cream27 products
25 products
hair color and bleaching23 products
shaving cream23 products
baby shampoo22 products
lip balm22 products
baby sunscreen22 products
baby soap19 products
eyelash glue17 products
detangler16 products
styling mousse/foam16 products
liquid hand soap15 products
lip plumper14 products
hair spray14 products
shaving cream (men's)13 products
beard care13 products
body spray11 products
antiperspirant/deodorant (men's)11 products
foot moisturizer11 products
after sun product10 products
sunless tanning10 products
eye makeup remover8 products
bubble bath8 products
after shave8 products
baby bubble bath7 products
baby wipes7 products
other eye makeup6 products
damaged skin treatment6 products
oil controller5 products
glitter4 products
muscle/joint soreness3 products
diaper cream3 products
bath oil/salts/soak3 products
foot odor control3 products
fragrance for women2 products
baby oil2 products
fragrance for men2 products
beard cleanser2 products
cuticle treatment2 products
bar soap2 products
body oil2 products
hand sanitizer2 products
lip balm with SPF2 products
nail treatment1 products
foot cleansing1 products
lip liner1 products
other men's products1 products
beard oil1 products
nail glue1 products
hair-loss treatment1 products
vapor rubs1 products
tanning oil1 products
body art1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling
Harmonized classification: this substance causes serious eye damage.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
Severe eye damage observed in animal testing.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
Classified as a mild skin irritant based on animal tests.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of eye toxicityCPS&Q - Classification & Labelling
Liver effects observed at low doses in repeat-dose studies in rats.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Allergies/immunotoxicity

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Concern Reference
Dermal sensitization has been reported in several human studies. Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
Contact dermatitis reported in human case reports.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Ecotoxicology

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Concern Reference
Harmonized classification: this substance is harmful to aquatic life with long lasting effects.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412

Data gaps

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Concern Reference
9 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 32 (S3): 5-21, 2013

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
  • Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • IJT 32 (S3): 5-21, 2013

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