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ETHYLHEXYLGLYCERIN

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate), Ecotoxicology (low), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation428 products
lipstick359 products
mask291 products
facial moisturizer/treatment269 products
eye shadow228 products
serums & essences223 products
moisturizer with SPF174 products
conditioner172 products
moisturizer165 products
bronzer/highlighter153 products
concealer141 products
beach & sport sunscreen136 products
facial cleanser104 products
facial powder92 products
shampoo83 products
blush80 products
eye liner64 products
body wash/cleanser62 products
mascara58 products
makeup primer56 products
brow liner53 products
lip gloss49 products
around-eye cream48 products
toners/astringents44 products
exfoliant/scrub44 products
hair styling aide42 products
hair treatment/serum40 products
styling gel/lotion34 products
antiperspirant/deodorant33 products
makeup remover30 products
CC cream30 products
hand cream29 products
hair color and bleaching26 products
body firming lotion26 products
anti-aging23 products
BB cream18 products
baby shampoo16 products
baby soap16 products
shaving cream16 products
baby sunscreen14 products
baby lotion12 products
detangler10 products
liquid hand soap10 products
lip balm10 products
styling mousse/foam9 products
shaving cream (men's)8 products
hair spray8 products
after shave7 products
sunless tanning7 products
bubble bath7 products
baby bubble bath6 products
other eye makeup6 products
foot moisturizer5 products
lip plumper4 products
eye makeup remover3 products
body spray3 products
oil controller3 products
beard care3 products
antiperspirant/deodorant (men's)3 products
after sun product3 products
bath oil/salts/soak2 products
nail treatment2 products
eyelash glue2 products
hand sanitizer2 products
lip balm with SPF2 products
glitter2 products
makeup with SPF1 products
foot cleansing1 products
fragrance for men1 products
foot odor control1 products
lip liner1 products
damaged skin treatment1 products
body art1 products
beard oil1 products
nail glue1 products
skin fading/lightener1 products
body oil1 products
bar soap1 products
muscle/joint soreness1 products
baby wipes1 products
cuticle treatment1 products
diaper cream1 products
baby oil1 products
vapor rubs1 products
other men's products1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling
Harmonized classification: this substance causes serious eye damage.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
Severe eye damage observed in animal testing.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
Classified as a mild skin irritant based on animal tests.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of eye toxicityCPS&Q - Classification & Labelling
Liver effects observed at low doses in repeat-dose studies in rats.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Allergies/immunotoxicity

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Concern Reference
Dermal sensitization has been reported in several human studies. Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
Contact dermatitis reported in human case reports.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Ecotoxicology

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Concern Reference
Harmonized classification: this substance is harmful to aquatic life with long lasting effects.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412

Data gaps

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Concern Reference
9 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 32 (S3): 5-21, 2013

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
  • Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • IJT 32 (S3): 5-21, 2013

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