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ETHYLHEXYLGLYCERIN

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Non-reproductive organ system toxicity (moderate), Ecotoxicology (low), and Irritation (skin, eyes, or lungs) (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW_MODERATE

Products with this Ingredient

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foundation849 products
lipstick565 products
facial moisturizer/treatment554 products
mask544 products
eye shadow465 products
moisturizer414 products
conditioner402 products
concealer397 products
serums & essences312 products
bronzer/highlighter310 products
facial cleanser291 products
daily use with SPF269 products
recreational sunscreen234 products
shampoo223 products
hair styling aide211 products
blush174 products
lip gloss167 products
mascara165 products
body wash/cleanser164 products
facial powder156 products
eye liner151 products
brow liner151 products
toners/astringents145 products
makeup primer145 products
exfoliant/scrub139 products
hair treatment/serum139 products
body firming lotion138 products
around-eye cream121 products
styling gel/lotion98 products
setting powder/spray94 products
CC cream85 products
hand cream83 products
antiperspirant/deodorant71 products
makeup remover60 products
baby lotion54 products
lip balm54 products
liquid hand soap48 products
eyelash glue45 products
body spray43 products
anti-aging42 products
hair color and bleaching41 products
BB cream40 products
baby sunscreen35 products
styling mousse/foam34 products
hair spray33 products
32 products
detangler31 products
baby shampoo30 products
shaving cream30 products
lip plumper25 products
after sun product24 products
baby soap22 products
beard care21 products
foot moisturizer17 products
antiperspirant/deodorant (men's)16 products
sunless tanning16 products
hand sanitizer15 products
glitter15 products
shaving cream (men's)13 products
bubble bath13 products
after shave12 products
muscle/joint soreness12 products
other eye makeup11 products
baby bubble bath11 products
eye makeup remover11 products
baby wipes9 products
lip liner9 products
bath oil/salts/soak8 products
body oil7 products
foot cleansing6 products
oil controller6 products
damaged skin treatment6 products
bar soap5 products
beard cleanser5 products
foot odor control4 products
skin fading/lightener3 products
diaper cream3 products
hair relaxer3 products
beard oil3 products
tanning oil3 products
nail treatment2 products
fragrance for women2 products
baby oil2 products
fragrance for men2 products
nail polish2 products
lip balm with SPF2 products
vapor rubs2 products
cuticle treatment1 products
body powder1 products
nail glue1 products
body art1 products

Irritation (skin, eyes, or lungs)

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Concern Reference
Classified as irritantCPS&Q - Classification & Labelling
Harmonized classification: this substance causes serious eye damage.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
Severe eye damage observed in animal testing.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
Classified as a mild skin irritant based on animal tests.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Organ system toxicity (non-reproductive)

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Concern Reference
Limited evidence of eye toxicityCPS&Q - Classification & Labelling
Liver effects observed at low doses in repeat-dose studies in rats.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Allergies/immunotoxicity

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Concern Reference
Dermal sensitization has been reported in several human studies. Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
Contact dermatitis reported in human case reports.Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;

Ecotoxicology

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Concern Reference
Harmonized classification: this substance is harmful to aquatic life with long lasting effects.EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412

Data gaps

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Concern Reference
9 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Informational

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Concern Reference
Industry or government recommendations for safe use: restrictions on concentration, impurities, product types, or manufacturing methods - anyIJT 32 (S3): 5-21, 2013

Data Sources

  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • EU GHS Hazard Labeling Codes 2012. GHS Hazard Codes. Appears as: Chemical Name: 3-(2-ethylhexyloxy)propane-1,2-diol; CAS number: 70445-33-9; Classification Hazard Statement Codes: H318|H412
  • Cosmetic Ingredient Review (CIR) 2015. CIR Assessments. Appears as: listid: CIR-3175; Chemical_Name: Ethylhexylglycerin; ; ; Classification: QQQ01;
  • Olivier Aerts, Lien Verhulst & An Goossens 2016. Ethylhexylglycerin: a low-risk, but highly relevant, sensitizer in
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • IJT 32 (S3): 5-21, 2013

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