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ETHANOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption and Non-reproductive organ system toxicity (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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serums & essences93 products
mask88 products
facial moisturizer/treatment82 products
lipstick77 products
hand sanitizer59 products
conditioner45 products
facial cleanser35 products
moisturizer32 products
moisturizer with SPF30 products
mouthwash28 products
shampoo27 products
toners/astringents26 products
lip gloss25 products
beach & sport sunscreen24 products
fragrance for women23 products
body wash/cleanser16 products
exfoliant/scrub16 products
eye liner16 products
foundation14 products
antiperspirant/deodorant13 products
around-eye cream13 products
mascara13 products
toothpaste12 products
body spray11 products
hair styling aide11 products
fragrance for men10 products
liquid hand soap9 products
shaving cream8 products
hand cream8 products
hair treatment/serum8 products
eye shadow7 products
body firming lotion7 products
brow liner7 products
hair spray6 products
makeup remover6 products
makeup primer6 products
lip balm5 products
hair color and bleaching5 products
concealer5 products
anti-aging4 products
after shave4 products
baby lotion4 products
oil controller4 products
styling gel/lotion3 products
bath oil/salts/soak3 products
baby sunscreen3 products
bar soap2 products
nail polish2 products
baby shampoo2 products
polish remover2 products
hair-loss treatment2 products
after sun product2 products
sunless tanning2 products
tooth whitening2 products
blush2 products
eye makeup remover2 products
Facial Sun Care2 products
bronzer/highlighter1 products
facial powder1 products
BB cream1 products
damaged skin treatment1 products
glitter1 products
Tanning Sprays1 products
bubble bath1 products
body oil1 products
makeup with SPF1 products
antiperspirant/deodorant (men's)1 products
detangler1 products
shaving cream (men's)1 products
diaper cream1 products
baby toothpaste1 products
beard oil1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Data gaps

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Concern Reference
334201 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

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