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ETHANOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption and Non-reproductive organ system toxicity (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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serums & essences108 products
foundation102 products
hand sanitizer95 products
facial moisturizer/treatment91 products
lipstick89 products
mask62 products
fragrance for women58 products
conditioner52 products
facial cleanser45 products
lip gloss41 products
moisturizer41 products
toners/astringents41 products
mouthwash40 products
fragrance for men35 products
shampoo32 products
eye liner30 products
moisturizer with SPF29 products
concealer28 products
hand cream25 products
body spray25 products
mascara21 products
beach & sport sunscreen20 products
exfoliant/scrub19 products
hair spray17 products
around-eye cream16 products
makeup primer16 products
body wash/cleanser14 products
brow liner14 products
hair styling aide14 products
antiperspirant/deodorant13 products
toothpaste12 products
liquid hand soap10 products
hair treatment/serum10 products
body firming lotion10 products
eye shadow9 products
bronzer/highlighter9 products
bath oil/salts/soak8 products
hair color and bleaching8 products
hair-loss treatment7 products
makeup remover7 products
shaving cream7 products
baby lotion6 products
6 products
oil controller5 products
anti-aging5 products
styling gel/lotion4 products
lip balm4 products
nail polish3 products
damaged skin treatment3 products
baby shampoo2 products
BB cream2 products
after shave2 products
foot moisturizer2 products
bar soap2 products
polish remover2 products
sunless tanning2 products
antiperspirant/deodorant (men's)2 products
blush2 products
eye makeup remover2 products
shaving cream (men's)1 products
facial powder1 products
after sun product1 products
body oil1 products
baby sunscreen1 products
baby toothpaste1 products
glitter1 products
tooth whitening1 products
detangler1 products
diaper cream1 products
eyelash glue1 products
bubble bath1 products
makeup with SPF1 products
beard oil1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Data gaps

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Concern Reference
334201 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

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