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ETHANOL

Score:

Data: Fair

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Enhanced skin absorption and Non-reproductive organ system toxicity (moderate)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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hand sanitizer177 products
serums & essences131 products
foundation121 products
facial moisturizer/treatment118 products
lipstick103 products
mask92 products
mouthwash69 products
fragrance for women63 products
conditioner63 products
facial cleanser62 products
moisturizer60 products
toners/astringents48 products
shampoo47 products
fragrance for men44 products
lip gloss41 products
daily use with SPF40 products
eye liner30 products
concealer29 products
recreational sunscreen28 products
antiperspirant/deodorant26 products
hand cream25 products
mascara24 products
liquid hand soap24 products
exfoliant/scrub23 products
body wash/cleanser22 products
makeup primer22 products
hair spray20 products
brow liner19 products
hair treatment/serum19 products
around-eye cream18 products
body firming lotion18 products
hair styling aide18 products
bath oil/salts/soak17 products
setting powder/spray13 products
eye shadow12 products
bronzer/highlighter12 products
toothpaste11 products
lip balm11 products
baby lotion9 products
hair color and bleaching9 products
makeup remover9 products
BB cream9 products
hair-loss treatment8 products
body spray8 products
nail polish8 products
8 products
shaving cream7 products
anti-aging6 products
styling gel/lotion5 products
bar soap5 products
sunless tanning5 products
oil controller5 products
bubble bath5 products
damaged skin treatment5 products
CC cream5 products
foot moisturizer4 products
polish remover4 products
baby shampoo4 products
antiperspirant/deodorant (men's)4 products
blush4 products
after shave3 products
tooth whitening3 products
baby soap3 products
after sun product3 products
eye makeup remover2 products
lip plumper2 products
nail treatment1 products
detangler1 products
shaving cream (men's)1 products
facial powder1 products
eyelash glue1 products
baby bubble bath1 products
body oil1 products
baby sunscreen1 products
baby toothpaste1 products
lip liner1 products
glitter1 products
beard oil1 products
baby wipes1 products

Enhanced skin absorption

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Concern Reference
Ethanol has been found to act as a penetration enhancer for many chemicals.Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Classified as medium human health priorityEnvironment Canada Domestic Substance List
Limited evidence of sense organ toxicityHarvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).

Miscellaneous

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Concern Reference
Occupational hazards related to handlingCPS&Q - Classification & Labelling

Data gaps

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Concern Reference
334201 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

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Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status

Persistence and bioaccumulation

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Concern Reference
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • Mutalik S, Udupa N "Effect of some penetration enhancers on the permeation of glibenclamide and glipizide through mouse skin." Pharmazie. 2003 Dec;58(12):891-4. ; Brand RM, Jendrzejewski JL, Henery EM, Charron AR. A single oral dose of ethanol can alter transdermal absorption of topically applied chemicals in rats. Toxicol Sci. 2006 Aug;92(2):349-55. Epub 2006 May 5.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
  • Harvell, J, M. Bason and H. Maibach. Contact Urticaria and its Mechanisms. Food Chemistry and Toxicology 32(2): 103-112. 1994. (Table 2: Substances identified as capable of causing contact urticaria).
  • CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.

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