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ENSULIZOLE

Score:

Data: Limited

  • Other Concerns
  • Functions
  • About the Chemical
  • Synonyms
  • Use restrictions (moderate) and Biochemical or cellular level changes (high)

Cancer

Cancer concern is LOW

Developmental & Reproductive Toxicity

Developmental & reproductive toxicity concern is LOW

Allergies & Immunotoxicity

Allergies & immunotoxicity concern is LOW

Products with this Ingredient

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moisturizer with SPF4 products
makeup primer2 products
makeup with SPF1 products

Biochemical or cellular level changes

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Concern Reference
Produces damaging reactive oxygen species upon exposure to sunlight{Stevenson, 1999}

Use restrictions

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Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Restricted in cosmetics (requirements) - use, concentration, or manufacturing restrictions - European Union - restricted for use in sunscreens - 8%SCCP 2006. Opinion concerning phenylbenzimidazole sufonic acid and its salts. Opinion: European Commission - The Scientfic Committee on Cosmetic Products and Non-Food Products Intended for Consumers. Available: http://ec.europa.eu/health/ph_risk/committees/04_sccp/sccp_opinions_en.htm

Cancer

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Concern Reference
Produces DNA strand breaks upon exposure to sunlight{Stevenson, 1999}

Data gaps

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Concern Reference
345 studies in PubMed science library may include information on the toxicity of this chemicalNLM PubMed

Ecotoxicology

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Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Irritation (skin, eyes, or lungs)

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Concern Reference
Not likely to be a skin irritant in humansSCCP 2006. Opinion concerning phenylbenzimidazole sufonic acid and its salts. Opinion: European Commission - The Scientfic Committee on Cosmetic Products and Non-Food Products Intended for Consumers. Available: http://ec.europa.eu/health/ph_risk/committees/04_sccp/sccp_opinions_en.htm

Organ system toxicity (non-reproductive)

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Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

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Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

  • {Stevenson, 1999}
  • Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
  • SCCP 2006. Opinion concerning phenylbenzimidazole sufonic acid and its salts. Opinion: European Commission - The Scientfic Committee on Cosmetic Products and Non-Food Products Intended for Consumers. Available: http://ec.europa.eu/health/ph_risk/committees/04_sccp/sccp_opinions_en.htm
  • NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
  • EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.

About this Ingredient's Score Range

  • Products with the EWG VERIFIED mark have met use restrictions and warnings based on EWG review of company data.

ABOUT THE SKIN DEEP® RATINGS

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

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Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. Learn more | Legal Disclaimer